Department of Neurosurgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Center for Diagnosis and Treatment of Cranial Nerve Diseases, Shanghai Jiao Tong University, Shanghai, China.
Department of Neurosurgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Center for Diagnosis and Treatment of Cranial Nerve Diseases, Shanghai Jiao Tong University, Shanghai, China.
World Neurosurg. 2019 May;125:e10-e15. doi: 10.1016/j.wneu.2018.12.035. Epub 2018 Dec 19.
Hemifacial spasm (HFS) is generally caused by the root exit zone of the facial nerve compressed by an overlying arterial loop. HFS can also be caused by various types of tumor, aneurysm, or arteriovenous malformation. We retrospectively analyzed patients to evaluate possible differences in the demographic and clinical features between primary and secondary HFS.
A retrospective study of 3140 cases of HFS treated in our department between January 2009 and June 2016. Among the 3140 total cases, 26 patients had secondary HFS.
The 26 tumors of secondary HFS included 11 meningiomas, 8 epidermoid cysts, and 7 vestibular schwannomas. Compared to those with idiopathic HFS, those patients with tumor-induced HFS were significantly younger (P < 0.05). Secondary HFS tended to have responsible vessels, and were observed in 20 (76.92%) of these 26 patients. The long-term effective rate of operation was 84% in the secondary HFS group and was 96.45% in the primary HFS group (P < 0.05); the incidence rate of complication was 12% in the secondary HFS group and was 3.06% in the primary HFS group (P < 0.05).
In cases of secondary HFS, facial nerves of most patients were compressed by blood vessels, so microvascular decompression after tumor resection plays an important role. We should examine the entire nerve root for possible vascular compression.
面肌痉挛(HFS)通常是由于面神经根部出颅区被上方动脉环压迫所致。HFS也可由各种类型的肿瘤、动脉瘤或动静脉畸形引起。我们回顾性分析了患者,以评估原发性和继发性 HFS 之间在人口统计学和临床特征方面可能存在的差异。
回顾性分析了我科 2009 年 1 月至 2016 年 6 月期间收治的 3140 例 HFS 患者。在这 3140 例患者中,有 26 例为继发性 HFS。
继发性 HFS 的 26 个肿瘤包括 11 例脑膜瘤、8 例表皮样囊肿和 7 例听神经瘤。与特发性 HFS 患者相比,肿瘤引起的 HFS 患者明显更年轻(P<0.05)。继发性 HFS 往往有责任血管,在这 26 例患者中有 20 例(76.92%)。继发性 HFS 组手术的长期有效率为 84%,原发性 HFS 组为 96.45%(P<0.05);继发性 HFS 组的并发症发生率为 12%,原发性 HFS 组为 3.06%(P<0.05)。
在继发性 HFS 中,大多数患者的面神经受到血管压迫,因此肿瘤切除后的微血管减压术发挥着重要作用。我们应该检查整个神经根,以确定是否存在可能的血管压迫。