Callow A D, Caplan L R, Correll J W, Fields W S, Mohr J P, Moore W S, Robertson J T, Toole J F
Department of Neurology, Tufts University School of Medicine, Boston, Massachusetts.
Am J Med. 1988 Dec;85(6):835-8. doi: 10.1016/s0002-9343(88)80030-5.
The plethora of recent articles regarding carotid endarterectomy has tended to confuse rather than clarify its indications, efficacy, and acceptability. The National Institutes of Health has recently funded two large multicenter controlled clinical trials, one including asymptomatic persons with carotid stenoses, and the other, patients having transient ischemic episodes or minor strokes. Eight academic professors of neurology (four), neurosurgery (two), and vascular surgery (two) with a long and abiding interest in cerebrovascular disease prepared a statement delineating acceptable levels of mortality and morbidity from this procedure. These might serve as guidelines until the large trials have been completed.
近期大量关于颈动脉内膜切除术的文章往往使人困惑，而非阐明其适应症、疗效及可接受性。美国国立卫生研究院最近资助了两项大型多中心对照临床试验，一项纳入有颈动脉狭窄的无症状者，另一项纳入有短暂性脑缺血发作或轻度中风的患者。八位长期关注脑血管疾病的神经学（四位）、神经外科（两位）和血管外科（两位）学术教授发表了一份声明，阐述了该手术可接受的死亡率和发病率水平。在大型试验完成之前，这些可作为指导原则。
