Wasserman G S
Poison Center, Children's Mercy Hospital, Kansas City, Missouri 64108.
Ann Emerg Med. 1988 Dec;17(12):1331-5. doi: 10.1016/s0196-0644(88)80360-3.
Venomous bites and stings are numerous but severe local tissue damage is uncommon. Venoms may be simple substances or complex mixtures of many poorly characterized components whose interactions are still not fully understood. The best studied example of a dermonecrotic venom is that produced by the brown recluse spider (Loxosceles reclusa). Rattlesnake envenomation also causes significant wound injuries. Many spider and snake envenomation management modalities are controversial and the evidence is mounting against the use of a number of these treatments.
毒蛇咬伤和虫蜇种类繁多，但严重的局部组织损伤并不常见。毒液可能是简单物质，也可能是由许多特性不明的成分组成的复杂混合物，其相互作用仍未完全了解。研究得最透彻的皮肤坏死性毒液的例子是棕色遁蛛（褐皮花蛛）产生的毒液。响尾蛇咬伤也会导致严重的伤口损伤。许多蜘蛛和蛇咬伤的处理方式存在争议，越来越多的证据反对使用其中一些治疗方法。
