鉴定和检测IV型葡萄球菌盒式染色体 mec 元件上ccrB2基因部分缺失的USA300耐甲氧西林金黄色葡萄球菌克隆株。
Identification and detection of USA300 methicillin-resistant Staphylococcus aureus clones with a partial deletion in the ccrB2 gene on the type IV SCCmec element.
作者信息
Takadama Shunsuke, Nakaminami Hidemasa, Takii Takemasa, Noguchi Norihisa
机构信息
Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan.
出版信息
Diagn Microbiol Infect Dis. 2019 May;94(1):86-87. doi: 10.1016/j.diagmicrobio.2018.11.016. Epub 2018 Nov 24.
Panton-Valentine leukocidin-positive highly pathogenic USA300 methicillin-resistant Staphylococcus aureus carries type IV staphylococcal cassette chromosome (SCC) mec. Here, we found USA300-like strains (named as ΨUSA300), which could not be identified as SCCmec type IV by the conventional PCR method due to a 12 bp deletion on ccrB2.
杀白细胞素阳性的高致病性美国300型耐甲氧西林金黄色葡萄球菌携带IV型葡萄球菌盒式染色体（SCC）mec。在此，我们发现了类似美国300型的菌株（命名为ΨUSA300），由于ccrB2上有12bp的缺失，通过传统PCR方法无法将其鉴定为IV型SCCmec。
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