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论慢性透析和肾移植的影响及需求。

On the impact of and need for chronic dialysis and renal transplantation.

作者信息

Kjellstrand C M, Shideman J

机构信息

Department of Medicine, Karolinska Hospital, Stockholm, Sweden.

出版信息

ASAIO Trans. 1988 Jul-Sep;34(3):328-33.

PMID:3058178
Abstract

The acceptance rate onto chronic dialysis is increasing linearly, but when expressed as a percentage of those in need the steepest increase occurred in the mid- and late 1970s; this increase is much slower now because the population dying of end-stage renal disease (ESRD) seems to be increasing as well. The increase in ESRD between 1960 and 1981 was 67%. Of this increase, 30% resulted from an increase in the population and 37% from an apparent increase in the incidence of ESRD. Transplant rate, as a percentage of patients accepted onto dialysis, has decreased because the number of patients on dialysis is increasing faster than available transplant kidney grafts. Almost all patients who are currently not accepted are older than the age of 60, and if they are accepted they will have a much shorter survival time than the present dialysis patient population. Although acceptance rate, as incidence per year, will probably continue to increase significantly, the prevalence figures of patients on chronic dialysis will probably increase less fast, as the patients will have shorter survival times. This overall shortening of survival time will probably be further shortened as transplanters increasingly transplant the younger patients who would have the longest survival times on dialysis.

摘要

慢性透析的接受率呈线性上升,但以有需求者的百分比表示时,最急剧的增长发生在20世纪70年代中后期;现在这种增长慢得多,因为死于终末期肾病(ESRD)的人数似乎也在增加。1960年至1981年间ESRD的增长为67%。在这一增长中,30%是由于人口增加,37%是由于ESRD发病率明显上升。移植率占接受透析患者的百分比有所下降,因为透析患者数量的增长速度快于可用移植肾的数量。目前几乎所有未被接受的患者年龄都在60岁以上,如果他们被接受,其存活时间将比目前的透析患者群体短得多。尽管接受率(每年的发病率)可能会继续显著上升,但慢性透析患者的患病率增长可能会较慢,因为患者的存活时间会较短。随着移植医生越来越多地移植那些在透析时存活时间最长的年轻患者,这种总体存活时间的缩短可能会进一步加剧。

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