Peng Yong, Wang Tingting, Wang Zhanqiu, Du Dan, Li Jinglong, Han Xiaoxiao, Liu Jianing, Wang Aidi, Zhou Xiangqian
Department of Biomedical Engineering, College of Electrical Engineering, Yanshan University, Qinhuangdao, Hebei 066004, P.R.China;Key Laboratory of National Defense of Mechanical Structure And Material Science Under Extreme Conditions, Yanshan University, Qinhuangdao, Hebei 066004,
Department of Biomedical Engineering, College of Electrical Engineering, Yanshan University, Qinhuangdao, Hebei 066004, P.R.China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2018 Dec 25;35(6):845-851. doi: 10.7507/1001-5515.201807059.
To solve the problem of precise positioning of carp brain tissue coordinates, it is proposed in this paper for a method for transforming the coordinates of magnetic resonance imaging of carp brain tissue into the coordinates of electrode implantation using a brain stereotaxic apparatus. In this study, the 3.0T magnetic resonance imaging instrument was used to scan the carp brain. We independently established the three-dimensional positioning coordinate system of the brain, the three-dimensional coordinate assistance system of skull surface and the three-dimensional coordinate assistance system in brain tissue. After two coordinate transformations, the magnetic resonance image coordinates of the brain electrodes implantation sites were converted into the three-dimensional stereotactic coordinate system to guide the electrodes implantation. The experimental groups were divided into two groups, A and B. Group A was the group of magnetic resonance imaging apparatus combining with the brain stereotaxic apparatus, and group B was the group of brain atlas combining with the brain stereotaxic apparatus. Each group had 20 tails of carps ( = 20). This two methods were used to implant the electrodes into the cerebellar motor area. The underwater experiments of the carp robots were carried out to test the two methods. The results showed that the accuracy of the implanted electrodes were 90% in group A and 60% in group B. The success rate of group A was significantly higher than that of group B ( < 0.05). Therefore, the new method in this paper can accurately determine the coordinates of carp brain tissue.
为解决鲤鱼脑组织坐标精确定位的问题，本文提出了一种利用脑立体定位仪将鲤鱼脑组织磁共振成像坐标转换为电极植入坐标的方法。在本研究中，使用3.0T磁共振成像仪对鲤鱼脑部进行扫描。我们自主建立了脑部三维定位坐标系、颅骨表面三维坐标辅助系统和脑组织内三维坐标辅助系统。经过两次坐标转换，将脑部电极植入部位的磁共振图像坐标转换为三维立体定位坐标系，以指导电极植入。实验组分为A、B两组。A组为磁共振成像仪结合脑立体定位仪组，B组为脑图谱结合脑立体定位仪组。每组有20尾鲤鱼（n = 20）。采用这两种方法将电极植入小脑运动区。对鲤鱼机器人进行水下实验以测试这两种方法。结果显示，A组电极植入准确率为90%，B组为60%。A组成功率显著高于B组（P < 0.05）。因此，本文中的新方法能够准确确定鲤鱼脑组织的坐标。
