Arora Karandeep Singh, Bansal Rahul, Mohapatra Shreeyam, Verma Akshay, Sharma Sakshi, Pareek Shubhangi
Department of Oral Medicine and Radiology, M. M. College of Dental Sciences and Research, Mullana, Ambala, Haryana, India. Email:
Asian Pac J Cancer Prev. 2018 Dec 25;19(12):3635-3641. doi: 10.31557/APJCP.2018.19.12.3635.
Objectives: The present observational study was conducted with an aim to evaluate the efficacy of diode laser in management of homogenous oral leukoplakia (OL) and reticular oral lichen planus (OLP), so that these potentially malignant disorders can be limited and further malignant transformation can be prevented. Further the assessment of associated postoperative complications after laser therapy was also carried out. Study Design: Present study was carried out using diode laser 810nm on 60 subjects, of whom 30 subjects were of homogenous OL and 30 subjects were of reticular OLP aged between 20 – 60 years, the diagnosis of which was histopathologically confirmed. Results: Of the 60 subjects none complained of pain during and immediately after surgery with no bleeding at any stage of the procedure. By the end of 3rd day post operative most subjects reported no pain and swelling and very few subjects had negligible pain and swelling when evaluated. On subsequent follow-up of 1,2 and 4 week(s) none of the subject reported of pain, swelling or bleeding and it was noted that all the areas treated with laser had healed without scarring with no signs of recurrence. Fibrosis was seen in two male patients and one female patient treated for OL and OLP respectively. Conclusion: Patient compliance and contentment without any postoperative complications were observed to be of high degree in the present study. Thus diode laser can be considered as a best alternative to conventional surgical treatment modality in managing OL and OLP and preventing its further transformation.
本观察性研究旨在评估二极管激光治疗均质型口腔白斑(OL)和网状口腔扁平苔藓(OLP)的疗效,从而限制这些潜在恶性疾病并预防进一步的恶变。此外,还对激光治疗后的相关术后并发症进行了评估。研究设计:本研究对60名受试者使用810nm二极管激光进行治疗,其中30名受试者为均质型OL,30名受试者为网状OLP,年龄在20至60岁之间,其诊断经组织病理学证实。结果:60名受试者中,无人在手术期间及术后立即抱怨疼痛,手术过程的任何阶段均无出血。术后第3天结束时,大多数受试者报告无疼痛和肿胀,评估时极少数受试者有轻微疼痛和肿胀。在随后1、2和4周的随访中,没有受试者报告疼痛、肿胀或出血,并且注意到所有接受激光治疗的区域均已愈合,无瘢痕形成,无复发迹象。分别接受OL和OLP治疗的两名男性患者和一名女性患者出现了纤维化。结论:在本研究中观察到患者的依从性和满意度较高,且无任何术后并发症。因此,在治疗OL和OLP并预防其进一步恶变方面,二极管激光可被视为传统手术治疗方式的最佳替代方法。