St George's Vascular Institute, St George's Hospital, London, United Kingdom.
St George's Vascular Institute, St George's Hospital, London, United Kingdom.
J Vasc Surg. 2019 Jul;70(1):43-52. doi: 10.1016/j.jvs.2018.09.065. Epub 2018 Dec 21.
The treatment of juxtarenal abdominal aortic aneurysms is challenging. Open surgical repair is not a viable option for many patients. The use of endovascular aneurysm sealing (EVAS) with chimney grafts (Ch-EVAS) has been proposed as an immediately available, off-the-shelf option for individuals with juxtarenal aneurysms who require urgent treatment or are unsuitable for fenestrated or branched devices. This study reports the outcomes from our first patients to undergo this procedure.
Data were collected prospectively for 62 consecutive patients undergoing Ch-EVAS at our institution. The procedures were undertaken for intact juxtarenal or suprarenal aneurysms in patients who were unfit for open repair or needed urgent treatment or when the aneurysm morphology was unsuitable for treatment with fenestrated or branched endografts.
Between July 2013 and June 2016, there were 62 patients who were treated with Ch-EVAS; 77.4% were male, and the mean age was 73.9 years. Median aneurysm diameter was 64.5 mm. Eight suprarenal aneurysms were treated, with three chimney grafts. Of 54 juxtarenal aneurysms treated, 21 cases used two chimney grafts and 33 cases used one chimney graft. Median follow-up was 407 days. Eleven patients underwent reintervention. There were five type IA endoleaks, all successfully treated. One type IB and one type II endoleak occurred, neither requiring treatment. There were four minor strokes. Chimney patency is 97%.
These results in a group of high-risk patients suggest that Ch-EVAS is a viable alternative to custom-made devices in patients who are unfit for open surgery. Longer term follow-up and data from the international registry will determine the widespread applicability and durability of this technique.
肾周腹主动脉瘤的治疗具有挑战性。许多患者不适合进行开放手术修复。使用烟囱支架的腔内动脉瘤封闭(EVAS)(Ch-EVAS)已被提出作为一种现成的、可立即使用的选择,适用于需要紧急治疗或不适合使用开窗或分支设备的肾周动脉瘤患者。本研究报告了我们首批接受该手术的患者的结果。
前瞻性收集了我院 62 例连续接受 Ch-EVAS 治疗的患者的数据。对于不适合开放修复或需要紧急治疗的患者,或动脉瘤形态不适合使用开窗或分支腔内移植物治疗的患者,进行了 Ch-EVAS 治疗,手术部位为完整的肾周或肾上动脉瘤。
2013 年 7 月至 2016 年 6 月,共有 62 例患者接受 Ch-EVAS 治疗;77.4%为男性,平均年龄为 73.9 岁。中位动脉瘤直径为 64.5mm。治疗了 8 例肾上动脉瘤,使用了 3 个烟囱支架。54 例肾周动脉瘤中,21 例使用 2 个烟囱支架,33 例使用 1 个烟囱支架。中位随访时间为 407 天。11 例患者接受了再次介入治疗。有 5 例 IA 型内漏,均成功治疗。出现 1 例 IB 型和 1 例 II 型内漏,均无需治疗。有 4 例轻微中风。烟囱支架通畅率为 97%。
在一组高危患者中,这些结果表明,在不适合开放手术的患者中,Ch-EVAS 是一种替代定制设备的可行选择。更长时间的随访和来自国际注册中心的数据将确定这项技术的广泛适用性和耐久性。