Koleade Adetola, Farrell Jamie, Mugford Gerald, Gao Zhiwei
Clinical Epidemiology Unit, Memorial University, Newfoundland and Labrador, Canada.
Faculty of Medicine, Health Sciences Centre (Respirology Department), Memorial University, St John's, Newfoundland and Labrador, Canada.
J Environ Public Health. 2018 Nov 21;2018:4657420. doi: 10.1155/2018/4657420. eCollection 2018.
Aboriginal peoples are at a higher risk of many chronic respiratory diseases compared to the general Canadian population. Patients with asthma-COPD overlap (ACO), a disease newly described in 2015, are associated with frequent exacerbations, rapid decline in lung function, poor quality of life, high mortality, and disproportionate utilization of health-care resources than patients with asthma and COPD alone. The objective was to investigate the prevalence and risk factors of ACO in Aboriginal peoples.
Data from the 2012 Aboriginal Peoples Survey (APS) were used for this study. The ACO definition was based on the respondent giving positive responses to both of the following questions and . Aboriginal peoples older than 45 years, women, widowed, separated, or divorced, having a total personal income below $20,000 were associated with a significant risk of ACO. Residing in Ontario, being a daily smoker, living in a rented dwelling, dwelling in need of major repairs, having diabetes, and working more than 40 hrs a week were also significantly associated with increased risk of ACO.
The results from this study will provide information to aid the development of prevention and intervention strategies for Aboriginal communities.
与加拿大普通人群相比,原住民患多种慢性呼吸道疾病的风险更高。哮喘 - 慢性阻塞性肺疾病重叠综合征(ACO)是2015年新描述的一种疾病,与哮喘和慢性阻塞性肺疾病(COPD)单独患者相比,ACO患者频繁发作、肺功能快速下降、生活质量差、死亡率高且医疗资源利用不成比例。目的是调查原住民中ACO的患病率及危险因素。
本研究使用了2012年原住民调查(APS)的数据。ACO的定义基于受访者对以下两个问题均给出肯定回答。45岁以上的原住民、女性、丧偶、分居或离婚、个人总收入低于20,000加元与ACO的显著风险相关。居住在安大略省、每日吸烟、居住在出租住所、住所需要大修、患有糖尿病以及每周工作超过40小时也与ACO风险增加显著相关。
本研究结果将为制定原住民社区的预防和干预策略提供信息。