Sałacki Andrzej Jakub, Wysokiński Andrzej
Doctoral Studies, II Faculty of Medicine with English Languae Divison, Medical University of Lublin.
Chair and Department of Cardiology, Medical University of Lublin.
Ann Agric Environ Med. 2018 Dec 20;25(4):602-604. doi: 10.26444/aaem/74196. Epub 2017 Jul 15.
Thrombocytosis is a disease where the platelet count exceeds 600,000/μl. It is usually reactive in nature, less often clonal. Reactive thrombocytosis is usually a response to reactive inflammation or infection, splenectomy, iron deficiency, pregnancy, physical effort or cancer.
The case is described of a heart attack with ST-segment elevation in a 19-year-old male which was occurred due to intensive haematopoietic system renewal, caused by frequent blood donation which, in turn, caused reactive thrombocytosis. Reactive thrombocytosis is very rarely the cause of heart attack with ST-segment elevation, and is extremely rarely caused by blood donation. It is generally considered that reactive thrombocytosis is not a risk factor in the case of thromboembolic complications.
The presented case and the literature point to the risk of serious thromboembolic incidents, including heart attack, in the course of thrombocytosis.
血小板增多症是一种血小板计数超过600,000/μl的疾病。其本质上通常是反应性的,克隆性的情况较少见。反应性血小板增多症通常是对反应性炎症或感染、脾切除术、缺铁、妊娠、体力活动或癌症的一种反应。
本文描述了一名19岁男性因频繁献血导致造血系统强烈更新,进而引发反应性血小板增多症,最终出现ST段抬高型心肌梗死的病例。反应性血小板增多症极少是ST段抬高型心肌梗死的病因,且极罕见由献血引起。一般认为,反应性血小板增多症在血栓栓塞并发症方面并非危险因素。
本病例及相关文献表明,血小板增多症过程中存在发生严重血栓栓塞事件(包括心肌梗死)的风险。