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药剂师干预对高血压患者疾病相关知识、用药依从性、健康相关生活质量及血压控制的影响

Impact of pharmacist's intervention on disease related knowledge, medication adherence, HRQoL and control of blood pressure among hypertensive patients.

作者信息

Amer Muhammad, Rahman Nisarur, Nazir Saeedur Rashid, Raza Atif, Riaz Humayun, Sultana Misbah, Sadeeqa Saleha

机构信息

Department of Pharmacy, COMSATS University Islamabad, Abbottabad Campus, Pakistan.

Faculty of Pharmacy, University of Sargodha, Sargodha, Pakistan.

出版信息

Pak J Pharm Sci. 2018 Nov;31(6 (Supplementary):2607-2616.

Abstract

The present study was aimed to evaluate the effect of educational intervention provided to the patients of hypertension through pharmacist with the goal to improve knowledge about hypertension, adherence to prescribed medicines, blood pressure control and HRQoL(Health Related Quality of Life).A total of 384 patients were assigned randomly into 2 groups including intervention and control groups each having 192 patients. Urdu versions of knowledge questionnaire regarding hypertension, medication adherence scale (MMAS-U) by Morisky and EuroQol scale (EQ-5D) were utilized. Each patient's blood pressure was measured. After educational intervention, an increase was found in mean knowledge score about hypertension (18.18 ± 4.00), adherence score (5.89 ± 1.90), HRQoL score (0.73 ± 0.12) and Visual Analogue Scale (VAS) score (69.39 ± 5.90) among the IG. The blood pressure control also improved and lower systolic (131.81 ± 10.98 mmHg) and diastolic blood pressures (83.75 ± 6.21 mmHg) were observed among the patients of IG. This study showed that educational programs are useful for patients in increasing patient's levels of knowledge about hypertension, improving adherence to prescribed medication and enhancing blood pressure control. This increase is in turn accountable to improve HRQoL.

摘要

本研究旨在评估通过药剂师对高血压患者进行教育干预的效果,目标是提高患者对高血压的认识、对处方药的依从性、血压控制水平以及健康相关生活质量(HRQoL)。总共384名患者被随机分为两组,即干预组和对照组,每组各有192名患者。使用了乌尔都语版的高血压知识问卷、Morisky的药物依从性量表(MMAS-U)和欧洲五维度健康量表(EQ-5D)。测量了每位患者的血压。教育干预后,干预组患者的高血压平均知识得分(18.18±4.00)、依从性得分(5.89±1.90)、健康相关生活质量得分(0.73±0.12)和视觉模拟量表(VAS)得分(69.39±5.90)均有所提高。血压控制情况也得到改善,干预组患者的收缩压(131.81±10.98 mmHg)和舒张压(83.75±6.21 mmHg)更低。本研究表明,教育项目对患者提高高血压知识水平、改善对处方药的依从性以及加强血压控制是有用的。这种提高反过来有助于改善健康相关生活质量。

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