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患者报告结局与临床医生报告结局在肿瘤学中常规监测的临床相关性

Clinical Relevance of Routine Monitoring of Patient-reported Outcomes Clinician-reported Outcomes in Oncology.

作者信息

Fiteni Frederic, Cuenant Alice, Favier Mireille, Cousin Christelle, Houede Nadine

机构信息

Department of Medical Oncology, University Hospital of Nimes, Nimes, France

Biometrics Unit, Institut du Cancer Montpellier, Montpellier, France.

出版信息

In Vivo. 2019 Jan-Feb;33(1):17-21. doi: 10.21873/invivo.11433.

Abstract

The National Cancer Institute Common Terminology Criteria for Adverse Events classification is the standard classification used by the physicians in oncology for reporting adverse events. This classification has evolved over the last years according to the emergence of new therapies. Reporting symptoms, quality of life (QoL) and toxicities via patient-reported outcomes (PROs) in clinical practice is not yet a standard of care, nevertheless many studies have been conducted recently to assess feasibility and impact of routine monitoring of PROs, which should enable for better management of toxicities and earlier detection of disease progression in a more patient-centered health care delivery system. The aim of this article was to discuss the advantages and limitations of both approaches, clinicians-reported outcomes and PROs. Growing evidence supports that the routine collection of PROs leads to improvement of QoL and overall survival of cancer patients.

摘要

美国国立癌症研究所不良事件通用术语标准分类是肿瘤学医生用于报告不良事件的标准分类。在过去几年中,随着新疗法的出现,这一分类不断演变。在临床实践中,通过患者报告结局(PROs)报告症状、生活质量(QoL)和毒性尚未成为一种标准治疗方式,不过最近已经开展了许多研究来评估PROs常规监测的可行性和影响,这应该能够在以患者为中心的医疗服务体系中更好地管理毒性并更早地发现疾病进展。本文的目的是讨论两种方法的优点和局限性,即临床医生报告结局和PROs。越来越多的证据支持,常规收集PROs可改善癌症患者的生活质量和总体生存率。

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本文引用的文献

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