Suppr超能文献

前房内注射利多卡因作为经典表面麻醉的补充用于缓解白内障手术中的眼痛。

Intracameral lidocaine as supplement to classic topical anesthesia for relieving ocular pain in cataract surgery.

作者信息

Nebbioso Marcella, Livani Maria Luisa, Santamaria Valentina, Librando Aloisa, Sepe Massimiliano

机构信息

Department of Sense Organs, Faculty of Medicine and Odontology, Sapienza University of Rome, Rome 00185, Italy.

S. Maria Goretti Hospital, via Guido Reni 1, Latina 04100, Italy.

出版信息

Int J Ophthalmol. 2018 Dec 18;11(12):1932-1935. doi: 10.18240/ijo.2018.12.09. eCollection 2018.

Abstract

AIM

To evaluate safety, efficacy, and patient adherence of intracameral lidocaine as supplement of classic topical anesthetic drops in cataract surgery.

METHODS

A prospective and controlled trial including a large cohort of 1650 individuals suffering with bilateral cataract not complicated, in program by phacoemulsification surgery, were randomly assigned to 2 different groups for the type of anesthesia received, 0.4% oxybuprocaine hydrochloride (INN) drops, and INN drops associated to intracameral 1% lidocaine hydrochloride monohydrate. At the end of surgery, tables were assigned to each patient indicating the degree of pain (0-3) felt during the operation.

RESULTS

Thirty-two percent of patients in group 1 declared to have not felt any pain against the 77% of patients in group 2. Fifty-nine percent of patients in group 1 complained about only a slight discomfort against 20% of group 2 patients. Only a small percentage of patients in group 1 (5%) admitted severe pain, while no patient in group 2 admitted severe pain. Four patients of group 2 reported an episode of transient amaurosis, lasting several hours after surgery.

CONCLUSION

Intracameral administration of lidocaine is a simple and secure method able to increase the analgesia during the cataract surgery, eliminating the discomfort and increasing also the cooperation of the patients during the steps of manipulation.

摘要

目的

评估前房内注射利多卡因作为经典表面麻醉滴眼液补充剂在白内障手术中的安全性、有效性和患者依从性。

方法

一项前瞻性对照试验,纳入了1650例患有双侧未合并并发症白内障的患者队列,这些患者计划接受超声乳化手术,根据所接受的麻醉类型随机分为2组,分别使用0.4%盐酸奥布卡因(国际非专利药品名称)滴眼液,以及与前房内注射1%一水合盐酸利多卡因联合使用的盐酸奥布卡因滴眼液。手术结束时,为每位患者填写表格,表明其在手术过程中感受到的疼痛程度(0 - 3级)。

结果

第1组32%的患者表示未感觉到任何疼痛,而第2组这一比例为77%。第1组59%的患者仅抱怨有轻微不适,而第2组这一比例为20%。第1组只有一小部分患者(5%)承认有剧痛,而第2组没有患者承认有剧痛。第2组有4名患者报告出现一过性黑矇,术后持续数小时。

结论

前房内注射利多卡因是一种简单且安全的方法,能够增强白内障手术期间的镇痛效果,消除不适,并在操作步骤中提高患者的配合度。

相似文献

1
Intracameral lidocaine as supplement to classic topical anesthesia for relieving ocular pain in cataract surgery.
Int J Ophthalmol. 2018 Dec 18;11(12):1932-1935. doi: 10.18240/ijo.2018.12.09. eCollection 2018.
2
A randomized clinical trial of combined topical-intracameral anesthesia in cataract surgery.
Ophthalmology. 1998 Nov;105(11):2007-11. doi: 10.1016/S0161-6420(98)91116-2.
6
Efficacy of topical plus intracameral anesthesia for cataract surgery in high myopia: randomized controlled trial.
J Cataract Refract Surg. 2008 Oct;34(10):1664-8. doi: 10.1016/j.jcrs.2008.06.019.
7
Topical tetracaine versus topical tetracaine plus intracameral lidocaine for cataract surgery.
J Cataract Refract Surg. 1998 Dec;24(12):1602-8. doi: 10.1016/s0886-3350(98)80350-7.
10
Topical anaesthesia alone versus topical anaesthesia with intracameral lidocaine for phacoemulsification.
Cochrane Database Syst Rev. 2007 Jul 18(3):CD005276. doi: 10.1002/14651858.CD005276.pub2.

引用本文的文献

2
Globe penetration during loco-regional anesthesia: prevalence and review of cases.
Int J Ophthalmol. 2022 Oct 18;15(10):1683-1690. doi: 10.18240/ijo.2022.10.18. eCollection 2022.
4
Topical anaesthesia plus intracameral lidocaine versus topical anaesthesia alone for phacoemulsification cataract surgery in adults.
Cochrane Database Syst Rev. 2020 Jul 28;7(7):CD005276. doi: 10.1002/14651858.CD005276.pub4.

本文引用的文献

1
Intraoperative and postoperative pain in cataract surgery.
Surv Ophthalmol. 2018 Jan-Feb;63(1):75-85. doi: 10.1016/j.survophthal.2017.07.002. Epub 2017 Jul 22.
2
The global state of cataract blindness.
Curr Opin Ophthalmol. 2017 Jan;28(1):98-103. doi: 10.1097/ICU.0000000000000340.
3
Transient complete visual loss after intracameral anesthetic injection in cataract surgery.
J Curr Ophthalmol. 2016 Feb 5;27(3-4):129-31. doi: 10.1016/j.joco.2015.12.005. eCollection 2015 Sep-Dec.
4
Role of Protease-Inhibitors in Ocular Diseases.
Molecules. 2014 Dec 8;19(12):20557-20569. doi: 10.3390/molecules191220557.
5
Local anesthetic lidocaine induces apoptosis in human corneal stromal cells in vitro.
Int J Ophthalmol. 2013 Dec 18;6(6):766-71. doi: 10.3980/j.issn.2222-3959.2013.06.05. eCollection 2013.
6
Role of dopaminergic receptors in glaucomatous disease modulation.
Biomed Res Int. 2013;2013:193048. doi: 10.1155/2013/193048. Epub 2013 Jun 26.
7
Toxicity of topical ophthalmic anesthetics.
Expert Opin Drug Metab Toxicol. 2013 Aug;9(8):983-8. doi: 10.1517/17425255.2013.794219. Epub 2013 Apr 25.
8
Acetazolamide-induced cilio-choroidal effusion after cataract surgery: unusual posterior involvement.
Drug Des Devel Ther. 2013;7:33-6. doi: 10.2147/DDDT.S38324. Epub 2013 Jan 23.
9
Cataract surgery complications: an in vitro model of toxic effects of ropivacaine and lidocaine.
Drugs R D. 2011 Dec 1;11(4):303-7. doi: 10.2165/11595120-000000000-00000.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验