Malagola Romualdo, Arrico Loredana, Giannotti Rossella, Pattavina Luigi
Department of Ophthalmology, University of Rome La Sapienza, Rome, Italy.
Drug Des Devel Ther. 2013;7:33-6. doi: 10.2147/DDDT.S38324. Epub 2013 Jan 23.
Idiosyncratic reactions to a large number of drugs have been reported to cause choroidal detachment and secondary angle-closure glaucoma (ACG). We report a case of bilateral acute ACG and peculiar choroidal effusion following administration of oral acetazolamide immediately after cataract surgery. Few cases of acute secondary ACG with choroidal effusion and anterior shift of the lens-iris diaphragm have been associated with acetazolamide compared with other sulfonamides. As far as we are aware, posterior involvement with retinal folds and papillary edema due to acetazolamide has not been described before.
据报道,大量药物的特异反应可导致脉络膜脱离和继发性闭角型青光眼(ACG)。我们报告了一例白内障手术后立即口服乙酰唑胺后发生双侧急性ACG和特殊脉络膜积液的病例。与其他磺胺类药物相比,很少有急性继发性ACG伴脉络膜积液和晶状体-虹膜隔前移的病例与乙酰唑胺有关。据我们所知,此前尚未有因乙酰唑胺导致视网膜褶皱和乳头水肿的后部受累情况的描述。