George Tonya C, Freet Daniel J, Cross James M, Huzar Todd F
At the John S. Dunn Burn Center at Memorial Hermann Hospital, part of the University of Texas Health Science Center at Houston, Tex., Tonya C. George is an assistant professor of surgery, Daniel J. Freet is an assistant professor, James M. Cross is a professor of surgery, and Todd F. Huzar is an associate professor of surgery. The authors have disclosed no potential conflicts of interest, financial or otherwise.
JAAPA. 2019 Jan;32(1):23-27. doi: 10.1097/01.JAA.0000547746.08181.f7.
Levamisole is a veterinary antihelminthic, chemotherapeutic agent, and immunomodulator that also is used as an adulterant and cutting agent in cocaine distribution. This drug may potentiate the sympathomimetic actions of cocaine and can cause neutropenia, agranulocytosis, purpuric retiform lesions, and skin necrosis. This article describes two cases of suspected levamisole-induced vasculitis. No standardized diagnostic or treatment algorithm exists for this challenging condition. Diagnosis and treatment require a multidisciplinary team approach.
左旋咪唑是一种兽医抗蠕虫药、化学治疗剂和免疫调节剂，也被用作可卡因分销中的掺杂物和切割剂。这种药物可能会增强可卡因的拟交感神经作用，并可导致中性粒细胞减少、粒细胞缺乏症、紫癜样网状病变和皮肤坏死。本文描述了两例疑似左旋咪唑诱发的血管炎病例。对于这种具有挑战性的病症，不存在标准化的诊断或治疗方案。诊断和治疗需要多学科团队协作。
Zotero 插件