Hallit Souheil, Hajj Aline, Shuhaiber Patricia, Iskandar Katia, Ramia Elsy, Sacre Hala, Salameh Pascale
Faculty of Medicine and Medical Sciences, Holy Spirit University of Kaslik (USEK), Jounieh, Lebanon.
INSPECT-LB: Institut National de Santé Publique, Epidémiologie Clinique et Toxicologie, Beirut, Lebanon.
J Eval Clin Pract. 2019 Apr;25(2):323-339. doi: 10.1111/jep.13082. Epub 2018 Dec 27.
Studies showed that pharmacists have little experience with adverse drug reactions (ADRs) reporting due to insufficient knowledge of the concept of ADR and pharmacovigilance (PV). There is an urge to assess hospital pharmacists' knowledge in medication safety practices.
To evaluate the knowledge, attitude, and practice, among hospital pharmacists in Lebanon concerning ADRs and PV concepts.
A cross-sectional study, conducted between March and July 2016, enrolled 187 hospital pharmacists in all Lebanese districts.
Concerning knowledge, 60.8% of the pharmacists said that ADR is an injury caused by appropriate and suboptimal care, while 74.6% of them said it can be preventable and nonpreventable. Moreover, 47.5% of them defined PV as being the study that detects, assesses, understands, and prevents adverse effects. Furthermore, 55.1% believed that PV concerns drug, herbal, medical devices, and vaccine problems. Concerning attitude, 61% of the pharmacists said they do not support direct ADR reporting by the patient. Of them, 78.6% confessed that ADR reporting is a professional obligation to them while 88.2% admitted that it is time-consuming with no outcome. When it comes to practice, 64.2% had been trained to report ADRs. Only 20.8% and 24.2% confessed reporting ADRs more than once a week, respectively. More than half (54.5%) said that they report the ADR to the patient's prescriber.
Lebanese hospital pharmacists have little knowledge about the concept and process of PV and spontaneous ADRs reporting system. However, these pharmacists have positive attitudes, but very little practice with reporting systems. Educational programs are urgently needed to emphasize the role and responsibility of pharmacists in PV practices and to raise awareness towards ADR reporting process.
研究表明，由于对药物不良反应（ADR）和药物警戒（PV）概念的了解不足，药剂师在ADR报告方面经验甚少。迫切需要评估医院药剂师在用药安全实践方面的知识。
评估黎巴嫩医院药剂师对ADR和PV概念的知识、态度及实践情况。
2016年3月至7月进行了一项横断面研究，纳入了黎巴嫩所有地区的187名医院药剂师。
在知识方面，60.8%的药剂师表示ADR是由适当和次优护理引起的伤害，而74.6%的药剂师表示ADR可预防和不可预防。此外，47.5%的药剂师将PV定义为检测、评估、理解和预防不良反应的研究。此外，55.1%的药剂师认为PV涉及药物、草药、医疗器械和疫苗问题。在态度方面，61%的药剂师表示他们不支持患者直接报告ADR。其中，78.6%承认ADR报告是他们的职业义务，而88.2%承认这既耗时又无结果。在实践方面，64.2%的药剂师接受过ADR报告培训。分别只有20.8%和24.2%的药剂师承认每周报告ADR超过一次。超过一半（54.5%）的药剂师表示他们会将ADR报告给患者的开处方医生。
黎巴嫩医院药剂师对PV概念和自发ADR报告系统的知识了解甚少。然而，这些药剂师态度积极，但在报告系统方面的实践很少。迫切需要开展教育项目，以强调药剂师在PV实践中的作用和责任，并提高对ADR报告过程的认识。
