Schillinger H, Traeder R, Klosa W, Pohl J
Universitäts-Frauenklinik, Freiburg.
Onkologie. 1988 Oct;11(5):216-20. doi: 10.1159/000216527.
In a retrospective study the diagnostic validity of sonography (US), computer-tomography (CT), scintigraphy (SC) and serum alkaline phosphatase (AP) in the detection of liver metastases was evaluated in 929 patients with malignant tumors: ovary (n = 367), mamma (n = 189), endometrium (n = 181), cervix (n = 162), fallopian tube (n = 10), vulva (n = 20). Definitive diagnosis was confirmed by autopsy (n = 51), surgical intervention (n = 297) or follow-up (n = 581). Specificity, sensitivity and overall accuracy of the different methods in the indication of liver metastasis were as follows: CT (n = 58) 81%, 98%, 93%, US (n = 929) 70%, 94%, 90%, SC (n = 512) 66%, 85%, 81%, AP (n = 325) 68%, 93%, 87%. In the last examination period, US and CT reached comparable results. In view of efficiency, AP and US would appear suitable for routine control in gynecological malignancies.
在一项回顾性研究中，对929例患有恶性肿瘤的患者（卵巢癌367例、乳腺癌189例、子宫内膜癌181例、宫颈癌162例、输卵管癌10例、外阴癌20例）进行了超声检查（US）、计算机断层扫描（CT）、闪烁扫描（SC）和血清碱性磷酸酶（AP）检测肝转移的诊断有效性评估。最终诊断通过尸检（51例）、手术干预（297例）或随访（581例）得以证实。不同方法在指示肝转移方面的特异性、敏感性和总体准确性如下：CT（58例）81%、98%、93%；US（929例）70%、94%、90%；SC（512例）66%、85%、81%；AP（325例）68%、93%、87%。在最后一个检查阶段，US和CT的结果相当。考虑到效率，AP和US似乎适用于妇科恶性肿瘤的常规检查。
