Moskvicheva Yu B, Gusev D V, Tabeeva G I, Chernukha G E
V.I. Kulakov Obstetrics, Gynecology and Perinatology National Medical Research Center of Ministry of Healthсаre of the Russian Federation, Moscow.
Vopr Pitan. 2018;87(1):85-91. doi: 10.24411/0042-8833-2018-10010. Epub 2017 Dec 18.
The assessment of nutrition status, anthropometry, eating disorders, fat tissue and leptin levels in 48 patients with functional hypothalamic amenorrhea (FHA) was conducted. The study of nutrition status revealed a discrepancy between the caloric intake and energy expenditure in 50% of patients, inadequate daily intake of carbohydrates in 91.7%, increased protein intake in 70.8% of patients. The recommended ratio of proteins, fats, carbohydrates in patients of the study group was not observed (1:1:0.3). It was noted that the deficit of adipose tissue and the decrease in serum leptin concentration were observed not only in patients with low body mass index), but also in 70% of women with normal values. Using the questionnaire Eating Disorder Inventory 2 (EDI-2) revealed that 54.2% of patients had drive for thinness and 22.9% of patients had body dissatisfaction. The results indicate the need for an integrated approach to the management of patients with FHA, which provides consultation of a gynecologist, psychotherapist and nutritionist.
对48例功能性下丘脑性闭经(FHA)患者的营养状况、人体测量学、饮食失调、脂肪组织和瘦素水平进行了评估。营养状况研究显示,50%的患者热量摄入与能量消耗存在差异,91.7%的患者每日碳水化合物摄入量不足,70.8%的患者蛋白质摄入量增加。研究组患者未观察到蛋白质、脂肪、碳水化合物的推荐比例(1:1:0.3)。值得注意的是,不仅体重指数较低的患者出现脂肪组织缺乏和血清瘦素浓度降低,70%体重正常的女性也出现了这种情况。使用饮食失调问卷2(EDI-2)发现,54.2%的患者有追求瘦身的倾向,22.9%的患者对自己的身体不满意。结果表明,需要采用综合方法来管理FHA患者,包括妇科医生、心理治疗师和营养师的会诊。