Huo Junsheng, Sun Jing, Chang Suying, Liu Kejun
National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Wei Sheng Yan Jiu. 2018 Sep;47(5):733-740.
To study on the cost-benefit from anemia reduction of 6-24 months infants in poor rural regions by Ying Yang Bao( YYB) intervention.
YYB was donated and distributed to 6-24 months infants in 8 counties in provinces of Sichuan, Gansu and Shaanxi. Total covered infants were 25 125 within them 1200 were sampled and measured hemoglobin levels and change of anemia prevalence in the baseline and after 1 year intervention. Total recovered infants number from anemia was calculated with decrease of anemia rate. The cost-benefit was analyzed with PROFILING and DALY models.
The total cost estimated was 6 134 871 RMB, average cost per person was 244 RMB among which costs of YYB, administration and manpower were 121 RMB, 104 RMB and 19 RMB respectively. After 1 year intervention, the anemia rate significantly declined from 52. 8 % to 26. 3 %. The recovered DALYs from present anemia and future cognition was 4863. 08 person·year. Benefit from 1 year YYB intervention in the counties was 69. 3065 million RMB from PROFILING model and60. 6874 million RMB from DALY model. The average cost of the intervention was 938. 46 RMB in saving 1 anemic and 1261. 52 RMB in saving 1 DALY loss in YYB intervention project. The cost-benefit ratio was 1 ∶ 10 at least. Sensitivity analysis showed stability of this cost-benefit analysis acceptable.
The nutrition intervention using YYB for poor rural region showed high economic benefit.
研究营养包（YYB）干预对贫困农村地区6 - 24月龄婴幼儿贫血改善的成本效益。
营养包由捐赠并发放至四川、甘肃和陕西三省8个县的6 - 24月龄婴幼儿。共覆盖婴幼儿25125名，从中抽取1200名测量其基线血红蛋白水平及贫血患病率，在干预1年后再次测量。根据贫血率的下降计算贫血恢复的婴幼儿总数。采用PROFILING和DALY模型分析成本效益。
估计总成本为6134871元人民币，人均成本为244元人民币，其中营养包、管理及人力成本分别为121元、104元和19元。干预1年后，贫血率从52.8%显著降至26.3%。当前贫血及未来认知方面恢复的伤残调整生命年（DALYs）为4863.08人年。根据PROFILING模型，各县营养包1年干预的效益为6930.65万元人民币，根据DALY模型为6068.74万元人民币。在营养包干预项目中，平均每改善1例贫血的干预成本为938.46元人民币，每避免1个DALY损失的干预成本为1261.52元人民币。成本效益比至少为1∶10。敏感性分析表明该成本效益分析的稳定性可接受。
营养包用于贫困农村地区的营养干预具有较高的经济效益。
