Park Kyung Duk, Hong Che Ry, Choi Jung Yoon, Kim Min Sun, Yi Eun Sang, Saysouliyo Sonephet, Phongsavath Khounthavy, Shin Hee Young
a Department of Pediatrics , Chonbuk National University College of Medicine , Jeonju , Republic of Korea.
b Department of Pediatrics , Seoul National University College of Medicine , Seoul , Republic of Korea.
Pediatr Hematol Oncol. 2018 May;35(4):268-275. doi: 10.1080/08880018.2018.1477888. Epub 2018 Dec 31.
The Lao-Korea National Children's Hospital initiated and developed a pediatric cancer treatment program for the first time in September 2012, through education by the Lee Jong-Wook project, establishment of infrastructure by the Korea International Cooperation Agency, and cooperation of medical staff.
we describe the experience of initiating and building this program by retrospectively reviewing the data from pediatric patients with cancer diagnosed at the Lao-Korea National Children's Hospital between September 2012 and December 2016.
A total of 78 patients diagnosed with acute lymphoblastic leukemia (ALL) (n = 44), acute myeloid leukemia (AML) (n = 12), chronic myeloid leukemia (n = 7), lymphoma (n = 6), retinoblastoma (n = 5), Wilms tumor (n = 3), and germ cell tumor (n = 1) were included. Of the 44 patients with ALL, 40 received induction chemotherapy, and 4 refused chemotherapy. Of these 40 patients, 29 (73.6%) achieved complete remission (CR) and 9 (22.5%) died during chemotherapy. Of the 29 patients with CR, 4 completed the chemotherapy, 19 were still on chemotherapy, 4 relapsed, and 2 were deceased. Treatment was unsuccessful for all 12 patients with AML.
We successfully initiated the pediatric cancer care program but faced challenges associated with high mortality because of insufficient resources. We should continue our efforts to find more abandoned patients, detect cancer earlier, and reduce the overall associated mortality.
老挝-韩国国立儿童医院于2012年9月首次启动并开展了儿童癌症治疗项目，该项目通过李钟郁项目的教育、韩国国际协力团的基础设施建设以及医务人员的合作得以实现。
我们通过回顾性分析2012年9月至2016年12月在老挝-韩国国立儿童医院确诊的儿童癌症患者的数据，来描述启动和建立该项目的经验。
共纳入78例患者，其中诊断为急性淋巴细胞白血病（ALL）（n = 44）、急性髓系白血病（AML）（n = 12）、慢性髓系白血病（n = 7）、淋巴瘤（n = 6）、视网膜母细胞瘤（n = 5）、肾母细胞瘤（n = 3）和生殖细胞瘤（n = 1）。在44例ALL患者中，40例接受了诱导化疗，4例拒绝化疗。在这40例患者中，29例（73.6%）达到完全缓解（CR），9例（22.5%）在化疗期间死亡。在29例CR患者中，4例完成了化疗，19例仍在化疗，4例复发，2例死亡。所有12例AML患者的治疗均未成功。
我们成功启动了儿童癌症护理项目，但由于资源不足面临着与高死亡率相关的挑战。我们应继续努力寻找更多被遗弃的患者，更早地发现癌症，并降低总体相关死亡率。
