Wohlgemuth S D, Clifford T G
Department of Surgery, Eastern Virginia Medical School, Norfolk.
South Med J. 1988 Dec;81(12):1569-70. doi: 10.1097/00007611-198812000-00025.
We have reported the case of a 47-year-old man who had massive splenomegaly and marked pancytopenia for which no cause was determined. Splenectomy produced dramatic improvement. The clinical, hematologic, and pathologic findings are characteristic of nontropical idiopathic splenomegaly, or Dacie's syndrome. In 20% of the 46 cases described in the literature, malignant lymphoma has subsequently developed.
我们报告了一例47岁男性病例，该患者有巨大脾肿大和明显全血细胞减少症，病因未明。脾切除术后病情显著改善。临床、血液学和病理学表现为非热带特发性脾肿大或达西综合征的特征。在文献报道的46例病例中，有20%随后发展为恶性淋巴瘤。
