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一期姑息治疗后法洛四联症的外科修复:右心室流出道支架置入术与改良布莱洛克-陶西格分流术对比

Surgical repair of Tetralogy of Fallot following primary palliation: Right ventricular outflow track stenting versus modified Blalock-Taussig shunt.

作者信息

Bigdelian Hamid, Ghaderian Mehdi, Sedighi Mohsen

机构信息

Department of Cardiovascular Surgery, School of Medicine, Isfahan University of Medical Science, Isfahan, Iran.

Pediatric Cardiology Research Center, Isfahan Cardiovascular Research Institute, Isfahan, Iran.

出版信息

Indian Heart J. 2018 Dec;70 Suppl 3(Suppl 3):S394-S398. doi: 10.1016/j.ihj.2018.06.020. Epub 2018 Jun 24.

Abstract

BACKGROUND

Tetralogy of Fallot (TOF) is a cyanotic disease requiring early intervention. We assessed the effect of right ventricular outflow tract (RVOT) stenting versus modified Blalock-Taussig shunt (mBTS) on outcomes of surgical repair of TOF.

METHODS

Fifteen palliated TOF infants underwent complete repair surgery. RVOT stenting was performed in seven infants and mBTS was done in eight infants. Data on sequential patients who underwent surgery were collected and reviewed retrospectively.

RESULTS

Stenting group were significantly younger (1.62±0.34 vs 2.80±0.52, p=0.001), had lower body weight (3.28±0.48 vs 5.03±0.67, p=0.001) and lesser body surface area (0.20±0.01 vs 0.26±0.20, p=0.001) than the mBTS group at palliation. Mean right pulmonary artery (RPA) diameter in stenting group at palliation was 2.9±0.54mm (z-score -3.08±0.97) and increased at surgery to 4.6±0.49mm (z-score -0.79±0.66) (p=0.001). The mean left pulmonary artery (LPA) diameter was 2.5±0.42mm (z-score -3.3±0.86), which increased to 3.3±0.40mm (z-score -2.2±0.74) at surgery (p=0.005). The mean RPA diameter in mBTS group at palliation was 3.2±0.32mm (z-score -2.9±0.70) and increased at surgery to 4.3±0.55mm (z-score -1.1±0.94) (p=0.001). The mean LPA diameter was 2.8±0.26mm (z-score -3.3±0.62), which increased to 3.2±0.24mm (z-score -2.4±0.52) at surgery (p=0.032). Repeat echocardiography showed significant increase in McGoon ratio and Nakata index in both groups (p=0.001). No significant differences were seen between the two groups regarding surgical procedure and postoperative complications.

CONCLUSION

RVOT stenting is a safe and effective approach instead of mBTS in hazardous TOF infants with hypercyanotic spell, small PAs and complex anatomies.

摘要

背景

法洛四联症(TOF)是一种需要早期干预的青紫型疾病。我们评估了右心室流出道(RVOT)支架置入术与改良布莱洛克 - 陶西格分流术(mBTS)对TOF手术修复结局的影响。

方法

15例姑息性TOF婴儿接受了完全修复手术。7例婴儿接受了RVOT支架置入术,8例婴儿进行了mBTS手术。回顾性收集并分析了接受手术的连续患者的数据。

结果

支架置入组在姑息治疗时明显比mBTS组年龄更小(1.62±0.34岁 vs 2.80±0.52岁,p = 0.001),体重更低(3.28±0.48 kg vs 5.03±0.67 kg,p = 0.001),体表面积更小(0.20±0.01 m² vs 0.26±0.20 m²,p = 0.001)。支架置入组在姑息治疗时右肺动脉(RPA)平均直径为2.9±0.54mm(z评分 -3.08±0.97),手术时增加到4.6±0.49mm(z评分 -0.79±0.66)(p = 0.001)。左肺动脉(LPA)平均直径为2.5±0.42mm(z评分 -3.3±0.86),手术时增加到3.3±0.40mm(z评分 -2.2±0.74)(p = 0.005)。mBTS组在姑息治疗时RPA平均直径为3.2±0.32mm(z评分 -2.9±0.70),手术时增加到4.3±0.55mm(z评分 -1.1±0.94)(p = 0.001)。LPA平均直径为2.8±0.26mm(z评分 -3.3±0.62),手术时增加到3.2±0.24mm(z评分 -2.4±0.52)(p = 0.032)。重复超声心动图显示两组的麦戈恩比率和中田指数均显著增加(p = 0.001)。两组在手术操作和术后并发症方面无显著差异。

结论

对于患有严重青紫发作、小肺动脉和复杂解剖结构的高危TOF婴儿,RVOT支架置入术是一种安全有效的方法,可替代mBTS。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c29/6309724/0811be188c7f/gr1.jpg

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