Richtig Erika
Department of Dermatology, Medical University of Graz, Auenbruggerplatz 8, 8036 Graz, Austria.
Memo. 2018;11(4):261-265. doi: 10.1007/s12254-018-0455-4. Epub 2018 Nov 20.
The 2018 ASCO Annual Meeting provided a closer look on the details of studies already presented. In melanoma, the interest was on neoadjuvant treatment options with high pathological response rates as well as updates on large phase III studies in stage IV disease. Further new targets were discussed focusing on additional drugs to a PD-1 backbone treatment. Another focus was on Merkel cell carcinoma and basal cell carcinomas, giving new data on PD-1 antibody treatments as well as on vismodegib as neoadjuvant therapy.
2018年美国临床肿瘤学会年会进一步探讨了已公布研究的细节。在黑色素瘤方面,关注点在于具有高病理缓解率的新辅助治疗方案以及IV期疾病大型III期研究的最新进展。还讨论了其他新靶点,重点是在PD-1基础治疗中添加其他药物。另一个重点是默克尔细胞癌和基底细胞癌,给出了关于PD-1抗体治疗以及维莫德吉作为新辅助治疗的新数据。