Lee Eunji, Ju Huiyeong, Jung Jong Hwa, Ikeda Mari, Habata Yoichi, Lee Shim Sung
Department of Chemistry and Research Institute of Natural Science , Gyeongsang National University , Jinju 52828 , South Korea.
Education Center, Faculty of Engineering , Chiba Institute of Technology , 2-1-1 Shibazono , Narashino , Chiba 275-0023 , Japan.
Inorg Chem. 2019 Jan 22;58(2):1177-1183. doi: 10.1021/acs.inorgchem.8b02549. Epub 2018 Dec 31.
Formation of a copper(I) iodide cluster based luminescent metal-organic frameworks (LMOFs) and its utilization for the detection of cysteine (Cys) in aqueous solution are reported. The reaction of bis(amidoquinoline) ligand (L) with copper(I) iodide afforded an LMOF {[(CuI)L]·2DMSO} (1) with a 4-sql topology linked by CuI clusters as a thermodynamic product. Time- and temperature-dependent PXRD experiments confirmed that the entire formation process for 1 is kinetically and thermodynamically controlled. Interestingly, LMOF 1 was also obtained under the mechanochemical condition. Moreover, LMOF 1 dispersed in water shows a selective quenching for Cys over other amino acids due to the strong affinity of Cys to copper(I) iodide. On the basis of the NMR data of L isolated from the decomposition of 1, the decomposition-displacement mechanism was proposed for the sensing of Cys. This result might be utilized for the practical detection of Cys because the sensing material can be prepared simply, and the sensing process is performed in aqueous media.
报道了一种基于碘化亚铜簇的发光金属有机框架（LMOF）的形成及其在水溶液中检测半胱氨酸（Cys）的应用。双（酰胺喹啉）配体（L）与碘化亚铜反应得到一种具有4-sql拓扑结构的LMOF {[(CuI)L]·2DMSO} （1），它以碘化亚铜簇为连接体，是一种热力学产物。时间和温度依赖性粉末X射线衍射实验证实，1的整个形成过程受动力学和热力学控制。有趣的是，在机械化学条件下也能得到LMOF 1。此外，由于半胱氨酸对碘化亚铜具有很强的亲和力，分散在水中的LMOF 1对半胱氨酸表现出比对其他氨基酸的选择性猝灭。根据从1的分解产物中分离出的L的核磁共振数据，提出了半胱氨酸传感的分解-置换机制。该结果可用于半胱氨酸的实际检测，因为传感材料制备简单，且传感过程在水性介质中进行。
