Ordienė Rasa, Orda Paulius, Vaškelytė Jolanta Justina, Stoškutė Neris, Kazakauskaitė Eglė, Benetis Rimantas, Punjabi Prakash P, Karčiauskas Dainius, Ereminienė Eglė
1 Department of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
2 Department of Cardiac, Thoracic and Vascular Surgery, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Perfusion. 2019 May;34(4):310-317. doi: 10.1177/0267659118820776. Epub 2018 Dec 31.
To evaluate the impact of concomitant tricuspid valve (TV) repair on the right ventricular (RV) function postoperatively and within the 6 months following degenerative mitral valve (MV) repair.
The prospective study included 37 patients (mean age 57.32 ± 2.13 years) with severe MV regurgitation due to primary MV prolapse. Nineteen underwent successful MV repair (TV(-) group). Additional TV repair due to moderate-to-severe TV regurgitation was performed in 18 (TV(+) group). Two-dimensional (2D) speckle-tracking and tissue Doppler echocardiography was performed for all patients before surgery and 7 days and 6 months after surgery.
Preoperative dimensions and indices of RV longitudinal function did not differ between the groups (right ventricle end-diastolic diameter (RVEDD) was 33.53 ± 0.94 mm vs. 34.67 ± 1.72 mm, tricuspid annular systolic motion (S') was 15.06 ± 0.85 cm/s vs. 16.0 ± 1.27 cm/s, tricuspid annular plane systolic excursion (TAPSE) was 24.02 ± 1.06 mm vs. 22.4 ± 1.36 mm, respectively; p>0.05). RVEDD decreased significantly and did not change within the follow-up in the TV(-) group. In the TV(+) group, RVEDD decreased early after surgery and more markedly six months later in comparison to the TV(-) group. Indices of RV systolic longitudinal function decreased early after surgery and had a tendency to increase after six months in both groups. Regional longitudinal strains of the lateral RV wall decreased early after surgery and improved within the six months in the TV(-) group and did not change significantly in the TV(+) group.
Additional TV repair in degenerative MV repair more markedly reduces RV dimensions and does not have a negative impact on RV systolic function in comparison to an isolated MV repair although these conclusions are of limited value due to the lack of a control group.
评估在退行性二尖瓣修复术后及术后6个月内同期进行三尖瓣修复对右心室功能的影响。
这项前瞻性研究纳入了37例因原发性二尖瓣脱垂导致严重二尖瓣反流的患者(平均年龄57.32±2.13岁)。19例患者成功进行了二尖瓣修复(三尖瓣阴性组)。另外18例因中重度三尖瓣反流进行了三尖瓣修复(三尖瓣阳性组)。对所有患者在手术前、术后7天和6个月进行二维斑点追踪和组织多普勒超声心动图检查。
两组术前右心室纵向功能的尺寸和指标无差异(右心室舒张末期直径分别为33.53±0.94mm和34.67±1.72mm,三尖瓣环收缩运动分别为15.06±0.85cm/s和16.0±1.27cm/s,三尖瓣环平面收缩期位移分别为24.02±1.06mm和22.4±1.36mm;p>0.05)。三尖瓣阴性组右心室舒张末期直径显著减小且在随访期间无变化。在三尖瓣阳性组中,右心室舒张末期直径在术后早期减小,与三尖瓣阴性组相比,6个月后减小更明显。两组右心室收缩纵向功能指标在术后早期均下降,6个月后有增加趋势。右心室外侧壁的区域纵向应变在术后早期下降,在三尖瓣阴性组6个月内有所改善,在三尖瓣阳性组无显著变化。
与单纯二尖瓣修复相比,在退行性二尖瓣修复中同期进行三尖瓣修复能更显著地减小右心室尺寸且对右心室收缩功能无负面影响,尽管由于缺乏对照组这些结论的价值有限。