Department of Cardio-Thoracic Surgery, Tanta University, Tanta, Egypt.
Department of Cardiac Surgery, Nasser Institute, Cairo, Egypt.
Heart Lung Circ. 2020 Oct;29(10):1554-1560. doi: 10.1016/j.hlc.2020.01.014. Epub 2020 Feb 29.
Surgical repair of concomitant functional moderate tricuspid valve (TV) regurgitation at the time of mitral valve (MV) surgery remains controversial.
The objective of this study was to evaluate the outcomes of concomitant repair of functional moderate tricuspid regurgitation (TR) during MV surgery for rheumatic valve disease.
From 1998 to 2016, 1,240 patients had rheumatic MV disease associated with moderate functional TR: 974 patients had MV surgery and concomitant TV repair (group 1) and 266 patients had MV surgery alone (group 2). Study endpoints were operative outcomes, rehospitalisation for congestive heart failure (CHF), and TV reintervention. Propensity score matching identified 192 well-matched pairs for outcomes comparison.
Patients who had concomitant TV repair were younger (p=0.02) and there were fewer diabetics (p=0.015). In matched patients, low cardiac output was significantly higher in group 2 (p=0.044) and there was no difference in ventilation time, intensive care unit stay, cardiopulmonary bypass, and ischaemic times (p=0.480, p=0.797, p=0.232, and p=0.550, respectively) between groups. Patients in group 2 required more TV reintervention (1 vs 35 in group 1 and 2, respectively; p=0.004) and rehospitalisation for CHF (5 vs 40 in group 1 and 2, respectively; p<0.001).
Concomitant TV repair for moderate TR in patients undergoing rheumatic MV surgery was not associated with increased operative risk. Postoperative low cardiac output syndrome and the risk of late TV reinterventions and rehospitalisation for CHF were lower with TV repair. Concomitant repair of the moderate TV regurgitation maybe beneficial for patients undergoing rheumatic MV surgery.
在二尖瓣(MV)手术时同时修复伴功能性中度三尖瓣(TV)反流仍然存在争议。
本研究旨在评估风湿性心脏瓣膜疾病患者 MV 手术时同时修复功能性中度三尖瓣反流(TR)的结局。
1998 年至 2016 年,共有 1240 例风湿性 MV 疾病合并中度功能性 TR 患者:974 例患者接受 MV 手术和同期 TV 修复(组 1),266 例患者仅接受 MV 手术(组 2)。研究终点为手术结果、充血性心力衰竭(CHF)再入院和 TV 再次介入。倾向评分匹配确定了 192 对匹配良好的患者进行结果比较。
同期 TV 修复组患者年龄较小(p=0.02),糖尿病患者较少(p=0.015)。在匹配患者中,组 2 的低心输出量明显更高(p=0.044),两组之间通气时间、重症监护病房停留时间、体外循环和缺血时间无差异(p=0.480、p=0.797、p=0.232 和 p=0.550)。组 2 患者需要更多的 TV 再次介入(1 例与组 1 和 2 中的 35 例分别;p=0.004)和 CHF 再入院(5 例与组 1 和 2 中的 40 例分别;p<0.001)。
风湿性 MV 手术患者中度 TR 同期 TV 修复与手术风险增加无关。TV 修复术后低心输出综合征和晚期 TV 再次介入和 CHF 再入院的风险较低。风湿性 MV 手术患者伴中度 TV 反流的同期修复可能对患者有益。