The University of Queensland, School of Public Health, Centre for Longitudinal and Life Course Research, Level 3, Public Health Building, Herston Road, Herston, Brisbane, Queensland 4006, Australia.
The University of Queensland, School of Public Health, Centre for Longitudinal and Life Course Research, Level 3, Public Health Building, Herston Road, Herston, Brisbane, Queensland 4006, Australia.
J Affect Disord. 2019 Mar 1;246:394-400. doi: 10.1016/j.jad.2018.12.106. Epub 2018 Dec 25.
Mental health symptoms are highly prevalent and dynamic among young people. Little is known about the trajectories of these symptoms and subsequent development of chronic conditions. This study examines whether (1) mental health trajectories can predict the onset of chronic conditions in young women and (2) trajectories are stronger predictors of the incidence of these conditions than mental health status measured at single time point.
6013 young Australian women were followed every 3-year for 20 years. The mental health trajectories in their 20s and mental health status 3-year before the onset of chronic conditions were used to predict the incidence of six chronic conditions in their 30s. Mental health trajectories were identified using latent mixture modelling of five-item Mental Health Index.
Five mental health trajectories were identified: maintaining a high score (high-stable); starting low then steadily increasing (improving); moderately high score, declining, then increasing (declining-improving); starting high then steadily decreasing (declining), and maintaining a low score (low-stable). In their 30s, 1015 (16.9%) women developed one or more conditions. The low-stable and declining groups were associated with increased odds of developing one or more conditions by 45% (odds ratio [OR] 1.45, 95% confidence interval [CI] 1.09-1.94) and 48% (OR 1.48, 95% CI 1.10-1.98), respectively, compared with the high-stable group. These are not so clearly distinguished by only considering mental health status at single time.
Self-reported chronic conditions.
Mental health symptom trajectories in women's 20s are associated with the onset of chronic physical conditions in their 30s.
精神健康症状在年轻人中普遍存在且动态变化。人们对这些症状的轨迹以及随后慢性疾病的发展知之甚少。本研究考察了(1)精神健康轨迹是否可以预测年轻女性慢性疾病的发生,以及(2)轨迹是否比单一时间点测量的精神健康状况更能预测这些疾病的发病率。
6013 名澳大利亚年轻女性在 20 年内每 3 年接受一次随访。她们 20 多岁时的精神健康轨迹和慢性疾病发生前 3 年的精神健康状况被用来预测她们 30 多岁时六种慢性疾病的发病率。使用五项目心理健康指数的潜在混合模型来确定精神健康轨迹。
确定了五种精神健康轨迹:保持高分(高稳定);开始得分低然后稳步增加(改善);中等高分,下降,然后增加(下降改善);开始得分高然后稳步下降(下降),并保持低分(低稳定)。在 30 多岁时,1015 名(16.9%)女性患上一种或多种疾病。低稳定组和下降组发生一种或多种疾病的可能性分别增加 45%(优势比 [OR] 1.45,95%置信区间 [CI] 1.09-1.94)和 48%(OR 1.48,95% CI 1.10-1.98),与高稳定组相比。仅考虑单一时间点的精神健康状况,这些差异并不明显。
自我报告的慢性疾病。
女性 20 多岁时的精神健康症状轨迹与 30 多岁时慢性身体疾病的发生有关。