Eby T L, Makek M S, Fisch U
Division of Otolaryngology, University of Alabama, Birmingham 35233.
Ann Otol Rhinol Laryngol. 1988 Nov-Dec;97(6 Pt 1):605-12. doi: 10.1177/000348948809700606.
Three cases of primary adenomas of the petrous bone are presented and compared to an adenoma arising from the external ear canal. In contrast to other adenomatous tumors, these caused slowly progressive inner ear symptoms without other signs, hence making differentiation from other benign lesions difficult. In one case, association with von Hippel-Lindau disease is suspected because of a strong family history and recent discovery of a similar lesion in the opposite ear. Bone destruction was found radiographically and clinically with vascular tumor tissue and cysts permeating the bone, causing adjacent bone destruction and remodeling. The histopathologic examination demonstrated this to be a benign process, however, with no direct tumor invasion or other signs of malignancy. Subtotal petrosectomy is a proven approach for complete removal of these tumors. Review of the literature revealed no previous reports of benign adenomas originating in the petrous bone.
本文报告了3例岩骨原发性腺瘤,并与1例外耳道腺瘤进行了比较。与其他腺瘤性肿瘤不同,这些肿瘤引起缓慢进展的内耳症状,无其他体征,因此难以与其他良性病变相鉴别。在1例病例中,由于家族病史强烈且近期在对侧耳发现类似病变,怀疑与冯·希佩尔-林道病有关。影像学和临床检查发现骨破坏,血管性肿瘤组织和囊肿浸润骨质,导致相邻骨质破坏和重塑。组织病理学检查显示这是一个良性过程,无直接肿瘤侵犯或其他恶性征象。岩骨次全切除术是完全切除这些肿瘤的有效方法。文献回顾显示,此前尚无岩骨起源的良性腺瘤的报道。