Department of Radiological Technology, Tsuchiya General Hospital, Hiroshima, Japan; Department of Diagnostic Radiology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.
Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Can Assoc Radiol J. 2019 May;70(2):181-185. doi: 10.1016/j.carj.2018.08.005. Epub 2018 Dec 29.
To evaluate the effect of sex, age, height, cardiac output (CO), total body weight (TBW), body surface area (BSA), and lean body weight (LBW) on vessel enhancement of the ascending aorta in pediatric chest computed tomography angiography (c-CTA).
This retrospective study received institutional review board approval; parental prior informed consent for inclusion was obtained for all patients. All 50 patients were examined using our routine protocol; iodine (600 mg/kg) was the contrast medium (CM). Unenhanced and contrast-enhanced scans were obtained. We calculated the CM volume per vessel enhancement and performed univariate and multivariate linear regression analysis of the relationship between CM volume per vessel enhancement and each of the body parameters.
All patient characteristics were significantly related to CM volume per vessel enhancement (P < .05). Multivariate linear regression analysis revealed a significant correlation between CM volume per vessel enhancement and TBW, BSA, and LBW, but not the patient sex, age, CO, and height. The LBW model for CM volume per vessel enhancement yielded the highest determination coefficient (R = .913) and the lowest Akaike Information Criterion (400.324).
Our findings support the delivery of an iodine dose adjusted to the LBW at c-CTA.
评估性别、年龄、身高、心输出量（CO）、总体重（TBW）、体表面积（BSA）和去脂体重（LBW）对儿科胸部 CT 血管造影（c-CTA）升主动脉血管增强的影响。
本回顾性研究获得了机构审查委员会的批准；所有患者均经父母事先知情同意纳入研究。所有 50 例患者均采用我们的常规方案进行检查；碘（600mg/kg）为造影剂（CM）。进行了未增强和增强扫描。我们计算了每支血管增强的 CM 体积，并对 CM 体积与每个身体参数之间的关系进行了单变量和多变量线性回归分析。
所有患者的特征均与 CM 体积与每支血管增强呈显著相关（P<.05）。多变量线性回归分析显示，CM 体积与 TBW、BSA 和 LBW 呈显著相关，但与患者性别、年龄、CO 和身高无关。CM 体积与 LBW 模型的决定系数（R=0.913）最高，Akaike 信息准则（400.324）最低。
我们的研究结果支持在 c-CTA 中根据 LBW 调整碘剂量。
