Saffari Fereshteh, Sobhanipoor Mohammad Hossein, Shahravan Arash, Ahmadrajabi Roya
Department of Microbiology and Virology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Faculty of Medicine, Microbiology Section, Bam University of Medical Sciences, Bam, Iran.
Infect Chemother. 2018 Dec;50(4):340-345. doi: 10.3947/ic.2018.50.4.340.
Frequent isolation of from root canal treated teeth with apical periodontitis, has proposed the role of this organism in endodontic treatment failures. Different factors have been suggested in the pathogenicity of this organism. In this study, 22 isolates from canals of root-filled teeth were identified, and phenotypic and genotypic characteristics were investigated. No resistance to vancomycin and gentamicin was noted, and most isolates (91%) were susceptible to ampicillin. Biofilm formation was detected in 73% of the isolates and may be considered as the most important virulence factor involved in the pathogenesis of these isolates.
从患有根尖周炎的根管治疗牙齿中频繁分离出[具体微生物名称未给出]，这表明该微生物在根管治疗失败中所起的作用。关于这种微生物的致病性，已经提出了不同的因素。在本研究中，对从根管充填牙齿的根管中分离出的22株[具体微生物名称未给出]进行了鉴定，并对其表型和基因型特征进行了研究。未发现对万古霉素和庆大霉素的耐药性，大多数分离株（91%）对氨苄西林敏感。在73%的分离株中检测到生物膜形成，这可能被认为是这些分离株发病机制中最重要的毒力因子。
