Sverrisdottir Unnur, Jonsdottir Freyja, Gunnarsdottir Anna Ingibjorg, Hardardottir Hildur, Bjarnadottir Ragnheidur Ingibjorg
Faculty of Pharmaceutical sciences, The University of Iceland.
Faculty of Pharmaceutical sciences, The University of Iceland, Pharmacy department, The National University Hospital.
Laeknabladid. 2019 Jan;105(1):11-16. doi: 10.17992/lbl.2019.01.211.
Evidence-based information regarding the use of medication during pregnancy is lacking, even though the use of medication during pregnancy is considered common and often neccesary. The aim of this study was to obtain reliable information on the use of medications during the first 20 weeks of pregnancy and the use of vitamins, minerals, fatty acids, herbs and other natural products. Women´s attitude and beliefs towards the use of medications was also examined.
The study was conducted at the Prenatal Diagnosis Unit at Landspitali from January to April 2017. Women who attended routine ultrasound examination at 20 weeks were offered to participate. A questionnaire was submitted to partici-pants in an interview with the researcher following the doctor's appointment.
Of the 213 participants, 90% used medication at least once during the first 20 weeks of pregnancy. Approximately 80% of these medications belong to FASS safety classes A and B and are considered safe during pregnancy. The proportion of women who did not use folic acid was 14% which was associated with residence in rural areas (p=0.03) and younger age (p=0.019). Natural products were used by 14% but information about their safety is lacking. The majority (81%) was satisfied with the information they received when a drug was prescribed and 94% said they had sufficient access to information about medication use during pregnancy. The most commonly used sources of information were the internet (51%) and the local midwive (44%).
The use of medications and supplements during pregnancy is common. Most medications being used are considered safe during pregnancy. The majority of pregnant women take folic acid. Pregnant women have a logical and generally a positive attitude towards medication use during pregnancy.
尽管孕期用药被认为很常见且常常是必要的，但缺乏关于孕期用药的循证信息。本研究的目的是获取关于妊娠前20周用药以及维生素、矿物质、脂肪酸、草药和其他天然产品使用情况的可靠信息。还研究了女性对用药的态度和信念。
该研究于2017年1月至4月在Landspitali的产前诊断科进行。邀请在20周时参加常规超声检查的女性参与。在预约医生后，研究人员在访谈中向参与者发放问卷。
在213名参与者中，90%在妊娠前20周至少使用过一次药物。这些药物中约80%属于FASS安全等级A和B，被认为在孕期是安全的。未使用叶酸的女性比例为14%，这与农村居住地区（p = 0.03）和年龄较小（p = 0.019）有关。14%的女性使用天然产品，但缺乏关于其安全性的信息。大多数（81%）对开药时获得的信息感到满意，94%的人表示她们有足够的途径获取孕期用药信息。最常用的信息来源是互联网（51%）和当地助产士（44%）。
孕期用药和补充剂很常见。大多数正在使用的药物在孕期被认为是安全的。大多数孕妇服用叶酸。孕妇对孕期用药持合理且总体积极的态度。
