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引流管的使用与结果的关联:一项基于全国膝关节置换术数据的人群研究。

Utilization of Drains and Association With Outcomes: A Population-Based Study Using National Data on Knee Arthroplasties.

机构信息

From the Institute for Healthcare Delivery Science, Department of Population Health Science and Policy (Dr. Poeran, Ms. Zubizarreta, and Dr. Mazumdar), Leni and Peter W. May Department of Orthopaedic Surgery (Dr. Poeran, Ms. Ippolito, Ms. Zubizarreta, Dr. Brochin, Dr. Galatz, and Dr. Moucha), and the Department of Medicine (Dr. Poeran), Icahn School of Medicine at Mount Sinai, New York, NY.

出版信息

J Am Acad Orthop Surg. 2019 Oct 15;27(20):e913-e919. doi: 10.5435/JAAOS-D-18-00408.

Abstract

INTRODUCTION

Although surgical drains have been used routinely in total knee arthroplasties (TKAs), results from several large trials have led to recommendations against their use. Because national data are lacking, we aimed at assessing utilization patterns of drains and perioperative outcomes in TKA procedures.

METHODS

We included 1,130,124 TKA procedures from the national claims-based Premier Healthcare Database (2006 to 2016). Patients receiving a drain were compared with those who did not. Multivariable multilevel models measured associations between drain use and blood transfusions, postoperative infections, 30-day readmission, and length/cost of hospitalization. Odds ratios and 95% confidence intervals are reported. Propensity score analyses were performed to assess the robustness of results.

RESULTS

Drain use decreased from 33.0% (n = 22,901 of 69,370) in 2006 to 15.6% (n = 19,418 of 124,440) in 2016 and was particularly higher in large (>500 beds; 27.1%) and nonteaching hospitals (26.9%). After adjustment for relevant covariates, the use of drains (compared with no use) was significantly associated with increases in particularly blood transfusions (odds ratio, 1.27; 95% confidence interval, 1.24 to 1.30 n = 138,306 total transfusions), whereas minimal effects were seen for other outcomes. Propensity score analyses confirmed these results.

DISCUSSION

Although retrospective, the current study provides an important insight into real-world clinical practice regarding the use of drains. With current evidence not supporting their use in TKA, we found that national utilization is slowly decreasing. Moreover, because drain use is associated with negative outcomes, future studies should focus on drivers of their continued use.

LEVEL OF EVIDENCE

Level III, therapeutic study.

摘要

简介

尽管在全膝关节置换术(TKA)中常规使用外科引流管,但几项大型试验的结果导致了不推荐使用引流管的建议。由于缺乏全国性数据,我们旨在评估 TKA 手术中引流管的使用情况和围手术期结果。

方法

我们纳入了来自全国基于索赔的 Premier Healthcare 数据库(2006 年至 2016 年)的 1,130,124 例 TKA 手术。接受引流管的患者与未接受引流管的患者进行了比较。多变量多层次模型测量了引流管使用与输血、术后感染、30 天再入院和住院时间/费用之间的关联。报告了比值比和 95%置信区间。进行倾向评分分析以评估结果的稳健性。

结果

引流管的使用从 2006 年的 33.0%(n = 69,370 例中的 22,901 例)下降到 2016 年的 15.6%(n = 124,440 例中的 19,418 例),在大型(>500 张床位;27.1%)和非教学医院(26.9%)中尤其较高。在调整了相关协变量后,与未使用引流管相比,使用引流管(n = 138,306 例总输血)与输血量增加显著相关(比值比,1.27;95%置信区间,1.24 至 1.30),而其他结果则影响较小。倾向评分分析证实了这些结果。

讨论

尽管是回顾性的,但本研究为 TKA 中引流管使用的真实临床实践提供了重要的见解。鉴于目前的证据不支持在 TKA 中使用引流管,我们发现全国范围内的使用率正在缓慢下降。此外,由于引流管的使用与负面结果相关,未来的研究应重点关注其继续使用的驱动因素。

证据水平

三级,治疗性研究。

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