Balto Julia M, Pilutti Lara A, Motl Robert W
Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Rehabil Nurs. 2019 Jan/Feb;44(1):52-59. doi: 10.1097/rnj.0000000000000128.
The prevalence and possible antecedents and correlates of loneliness in multiple sclerosis (MS) was examined.
Cross-sectional, comparative study of MS (n = 63) and healthy adults (n = 21).
Data were collected using self-reports of loneliness and antecedents and correlates and analyzed using inferential statistics.
Those with MS had significantly higher loneliness scores than healthy adults (p < .05), and this was explained by employment status. Possible antecedents included marital status (p < .05), upper extremity function (r= -.28, p < .03), social disability frequency (r= -.49, p < .00), social disability limitations (r= -.38, p < .00), and personal disability limitations (r= -.29, p < .03). Social disability frequency (beta = -.41, p < .001) and marital status (beta = -.23, p < .046) accounted for 25% of the variance in loneliness scores. Possible correlates included depression (r= .49, p < .00), cognitive fatigue (r= .34, p < .01), psychosocial fatigue (r= .30, p < .02), and psychological quality of life (r= .44, p < .00).
We provide evidence of loneliness in persons with MS, and this is associated with possible antecedents (e.g., marital status and disability limitations) and correlates (e.g., depression and fatigue).
Loneliness should be recognized clinically as an important concomitant of MS.
研究多发性硬化症（MS）患者孤独感的患病率及其可能的前驱因素和相关因素。
对63例MS患者和21名健康成年人进行横断面比较研究。
通过孤独感及其前驱因素和相关因素的自我报告收集数据，并使用推断统计进行分析。
MS患者的孤独感得分显著高于健康成年人（p < 0.05），这可以通过就业状况来解释。可能的前驱因素包括婚姻状况（p < 0.05）、上肢功能（r = -0.28，p < 0.03）、社交障碍频率（r = -0.49，p < 0.00）、社交障碍限制（r = -0.38，p < 0.00）和个人残疾限制（r = -0.29，p < 0.03）。社交障碍频率（β = -0.41，p < 0.001）和婚姻状况（β = -0.23，p < 0.046）解释了孤独感得分变异的25%。可能的相关因素包括抑郁（r = 0.49，p < 0.00）、认知疲劳（r = 0.34，p < 0.01）、心理社会疲劳（r = 0.30，p < 0.02）和心理生活质量（r = 0.44，p < 0.00）。
我们提供了MS患者存在孤独感的证据，且这与可能的前驱因素（如婚姻状况和残疾限制）及相关因素（如抑郁和疲劳）有关。
临床上应认识到孤独感是MS的一个重要伴随症状。
