Suppr超能文献

两例下颌骨转移的病例报告。

Two case reports on Mandibular metastases.

作者信息

Adewale Adesina O, Mofoluwake Ladeji A, Olamide Opaleye T, Yussuf Salami A

机构信息

Department of Oral & Maxillofacial Surgery, Faculty of Dentistry, Lagos State University College of Medicine, Lagos State, Nigeria.

Department of Oral Pathology, Faculty of Dentistry, Lagos State University College of Medicine, Lagos State, Nigeria.

出版信息

Ghana Med J. 2018 Sep;52(3):168-172. doi: 10.4314/gmj.v52i3.11.

Abstract

Metastatic tumours of the oral cavity are not common. The most common site for bone metastases in the head and neck region is the mandible. Metastatic lesion of the mandible most commonly originate from the lungs in men and breast in women, and these lesions (or tumours) usually are carcinomas rather than sarcomas. We report two cases of metastatic lesions in the mandible: (1) A 19year old male with right mandibular swelling and a nodular swelling in the distal two-third of the right tibia. Radiograghs revealed sclerotic lesion with a sunburst appearance in both the jaw and tibia. Histology of the jaw lesion confirmed a metastatic osteosarcoma of the mandible. (2) A 51year old female with a right mandibular swelling with associated swelling in the anterior neck, right shoulder and right parietal region of the skull. Computerised tomography scan (CT) of the jaws showed an osteolytic lesion of the right mandible. CT scan of the brain also showed a large lytic lesion seen in the posterior aspect of the right parietal bone. Histology of the jaw mass confirmed a metastatic follicular carcinoma from the thyroid. Mandibular metastasis may be the first presenting feature of underlying occult malignancy of another primary site. Therefore, clinicians should maintain a high level of suspicion while evaluating patients with a history of cancer presenting with oral lesions.

摘要

口腔转移性肿瘤并不常见。头颈部骨转移最常见的部位是下颌骨。下颌骨转移性病变在男性中最常起源于肺部,在女性中最常起源于乳腺,并且这些病变(或肿瘤)通常是癌而非肉瘤。我们报告两例下颌骨转移性病变:(1)一名19岁男性,右下颌肿胀,右胫骨远端三分之二处有结节状肿胀。X线片显示颌骨和胫骨均有呈日光放射状外观的硬化性病变。颌骨病变的组织学检查证实为下颌骨转移性骨肉瘤。(2)一名51岁女性,右下颌肿胀,伴有颈部前方、右肩部和颅骨右顶叶区域肿胀。颌骨计算机断层扫描(CT)显示右下颌骨有溶骨性病变。脑部CT扫描还显示右顶骨后部有一个大的溶骨性病变。颌骨肿物的组织学检查证实为来自甲状腺的转移性滤泡癌。下颌骨转移可能是另一原发部位潜在隐匿性恶性肿瘤的首发表现。因此,临床医生在评估有癌症病史且出现口腔病变的患者时应保持高度怀疑。

相似文献

1
Two case reports on Mandibular metastases.两例下颌骨转移的病例报告。
Ghana Med J. 2018 Sep;52(3):168-172. doi: 10.4314/gmj.v52i3.11.
2
Metastasis of thyroid carcinoma to the mandible. Case report.甲状腺癌转移至下颌骨。病例报告。
Aust Dent J. 1999 Mar;44(1):56-7. doi: 10.1111/j.1834-7819.1999.tb00537.x.
3
Metastatic follicular thyroid carcinoma to the mandible.下颌骨转移性滤泡状甲状腺癌。
Indian J Dent Res. 2012 Nov-Dec;23(6):843. doi: 10.4103/0970-9290.111292.
4
Metastatic follicular thyroid carcinoma: a case report.
Gerodontology. 2017 Jun;34(2):276-279. doi: 10.1111/ger.12240. Epub 2016 Jul 7.
10
Mandibular osteoblastic metastasis of poorly differentiated carcinoma of the thyroid gland.下颌骨成骨型甲状腺癌骨肉瘤转移。
Int J Oral Maxillofac Surg. 2010 Mar;39(3):301-4. doi: 10.1016/j.ijom.2009.10.014. Epub 2009 Nov 25.

本文引用的文献

1
Metastatic tumors to the jaws and mouth.转移至颌骨和口腔的肿瘤。
Head Neck Pathol. 2014 Dec;8(4):463-74. doi: 10.1007/s12105-014-0591-z. Epub 2014 Nov 20.
2
Numb chin syndrome: an ominous clinical sign.麻木下巴综合征:一个凶险的临床征象。
Br Dent J. 2010 Apr 10;208(7):283-5. doi: 10.1038/sj.bdj.2010.292.
4
Gnathic bone metastasis: a retrospective study of 10 cases.颌骨转移瘤:10例回顾性研究
Braz J Otorhinolaryngol. 2008 Jul-Aug;74(4):561-5. doi: 10.1016/s1808-8694(15)30603-0.
5
Metastatic tumors in the jaws: a retrospective study of 114 cases.颌骨转移性肿瘤:114例回顾性研究
J Am Dent Assoc. 2006 Dec;137(12):1667-72. doi: 10.14219/jada.archive.2006.0112.
7
METASTATIC CARCINOMA OF THE JAWS.颌骨转移性癌
Acta Pathol Microbiol Scand. 1963;57:361-74. doi: 10.1111/j.1699-0463.1963.tb05105.x.
8
Metastatic carcinoma of the mandibular condyle.
Oral Surg Oral Med Oral Pathol. 1956 Dec;9(12):1318-23. doi: 10.1016/0030-4220(56)90233-x.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验