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灼口综合征——一个诊断难题。

Burning mouth syndrome-a diagnostic dilemma.

机构信息

Cork University Dental School and Hospital, Wilton, Cork, Ireland.

Eastman Dental Institute, London, UK.

出版信息

Ir J Med Sci. 2019 Aug;188(3):731-734. doi: 10.1007/s11845-018-01960-y. Epub 2019 Jan 2.

Abstract

BACKGROUND

Burning mouth syndrome (BMS) is a chronic pain disorder, more common in peri and postmenopausal females, with a varied symptomatology. Symptoms include a burning or stinging sensation of the tongue, lips or other oral mucosal surfaces, subjectively dry mouth or excess saliva, altered taste or loss of taste and paraesthetic sensations. These are usually present daily for more than 3 months.

AIMS

The aims of this study were to highlight the symptomatic manifestations of BMS along with the need for prompt diagnosis and onward referral when necessary.

METHODS

A cross-sectional study of patients with idiopathic BMS was conducted. The presenting symptoms, time to diagnosis and number of clinicians seen in advance of a diagnosis of BMS and anxiety and depression as determined by the Hospital Anxiety and Depression Scale (HADS) was recorded. Correlations were explored.

RESULTS

Fifty patients were enrolled in this study (38, F:12, M). The average time from onset of symptoms to diagnosis was 13 months. Commonly reported symptoms included burning (n = 44) and altered taste (n = 14). The median anxiety score was 13 and the median depression score was 10. No statistically significant correlations were found between the anxiety and depression scores generated and the number of clinicians seen or the time to diagnosis.

CONCLUSION

The results of this study indicate that there is a need for an increased awareness of the symptoms reported in BMS, particularly in peri and postmenopausal women. This should aid prompt diagnosis and may alleviate some of the anxiety that patients may experience.

摘要

背景

灼口综合征(BMS)是一种慢性疼痛障碍,多见于绝经前后的女性,其症状多种多样。症状包括舌、唇或其他口腔黏膜表面的烧灼感或刺痛感、主观口干或唾液过多、味觉改变或丧失以及感觉异常。这些症状通常每天持续超过 3 个月。

目的

本研究旨在强调 BMS 的症状表现,并强调在需要时及时诊断和转介。

方法

对特发性 BMS 患者进行横断面研究。记录患者的主要症状、诊断时间以及在诊断 BMS 之前就诊的医生数量、采用医院焦虑抑郁量表(HADS)评估的焦虑和抑郁情况。并对相关性进行了探讨。

结果

本研究共纳入 50 例患者(38 例女性,12 例男性)。从症状出现到诊断的平均时间为 13 个月。常见的症状包括烧灼感(n=44)和味觉改变(n=14)。焦虑评分中位数为 13,抑郁评分中位数为 10。焦虑和抑郁评分与就诊医生数量或诊断时间之间无统计学显著相关性。

结论

本研究结果表明,需要提高对 BMS 报告症状的认识,特别是在绝经前后的女性中。这有助于及时诊断,并可能减轻患者的一些焦虑。

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