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胃肠道和皮肤病主诉患者中芽囊原虫病的患病率及芽囊原虫密度对症状学的影响

The Prevalance of Blastocystosis among Patients with Gastrointestinal and Dermatologic Complaints and Effects of Blastocystis spp. Density on Symptomatology.

作者信息

Tunalı Varol, Öztürk Eylem Akdur, Ünver Ayşegül, Turgay Nevin

机构信息

Ege Üniversitesi Tıp Fakültesi, Tıbbi Parazitoloji Ana Bilim Dalı, İzmir, Türkiye.

出版信息

Turkiye Parazitol Derg. 2018 Dec;42(4):254-257. doi: 10.5152/tpd.2018.5702.

DOI:10.5152/tpd.2018.5702
PMID:30604685
Abstract

OBJECTIVE

Blastocystosis has been linked with non-specific symptoms, such as diarrhea, abdominal pain, and distention. In this study, we evaluated the relationship between Blastocystis spp. with urticaria and intestinal symptoms.

METHODS

The results of the stool examinations of the patients who were referred to Ege University Medical Faculty Hospital's Medical Parasitology Department Direct Diagnosis Laboratory with gastrointestinal (GIS) and/or dermatologic symptoms between January 2011 and July 2016 were retrospectively scanned.

RESULTS

Of the evaluated 37108 stool samples, 2573 (6.93 %) were identified to be positive for Blastocystis spp. The patients with gastrointestinal complaints comprised 68.4% of Blastocystis spp. positive samples (1.761 samples) while 30.1% of patients had dermatologic symptoms (urticaria) (776 samples). Blastocystis spp. density in the non-amplified (without using any stool concentration technique) stool samples of the patients with GIS and dermatological symptoms was as follows: 2.47%, 1.35% rare, 21.73%, 22.17% few, 49.65%, 54.29% medium, 26.27%, and 22.17% dense, respectively.

CONCLUSION

75.92% and 76.46% of the patients with GIS and dermatological complaints had medium to dense parasite densities in their stool samples respectively. This suggests a positive correlation between parasite density and GIS and dermatologic symptomatology.

摘要

目的

芽囊原虫病与腹泻、腹痛和腹胀等非特异性症状有关。在本研究中,我们评估了芽囊原虫属与荨麻疹及肠道症状之间的关系。

方法

回顾性分析2011年1月至2016年7月期间因胃肠道(GIS)和/或皮肤病症状转诊至伊兹密尔埃杰大学医学院医院医学寄生虫学系直接诊断实验室的患者的粪便检查结果。

结果

在评估的37108份粪便样本中,有2573份(6.93%)被鉴定为芽囊原虫属阳性。有胃肠道症状的患者占芽囊原虫属阳性样本的68.4%(1761份样本),而30.1%的患者有皮肤病症状(荨麻疹)(776份样本)。有GIS和皮肤病症状的患者未扩增(未使用任何粪便浓缩技术)粪便样本中的芽囊原虫属密度如下:分别为2.47%、1.35%稀少、21.73%、22.17%少量、49.65%、54.29%中等、26.27%和22.17%密集。

结论

有GIS和皮肤病症状的患者中,分别有75.92%和76.46%的患者粪便样本中的寄生虫密度为中等至密集。这表明寄生虫密度与GIS和皮肤病症状之间存在正相关。

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