Department of Nutrition, Food, and Exercise Sciences, Institute of Sports Sciences & Medicine, Florida State University , Tallahassee, Florida.
Department of Kinesiology, Korey Stringer Institute, University of Connecticut , Storrs, Connecticut.
J Appl Physiol (1985). 2019 Mar 1;126(3):739-745. doi: 10.1152/japplphysiol.00752.2018. Epub 2019 Jan 3.
This study investigated the effect of acute full-body resistance exercise [RE; one set of 10 repetitions at 40% 1 repetition maximum (1RM) and three sets of 10 repetitions at 65% 1RM] on subcutaneous abdominal adipose tissue (SCAAT) lipolysis and whole body substrate oxidation in young (age: 22 ± 1 yr), normal-weight and body fatness (body mass index: 20 ± 1 kg/m; %body fat: 28.7 ± 1.4%), resistance-trained women. Microdialysis was used to measure SCAAT lipolysis at baseline, mid-RE, post-RE, and 30 min post-RE, and indirect calorimetry was used to measure whole body substrate oxidation at baseline and immediately post-RE in 13 women. Plasma concentrations of glucose, insulin, nonesterified fatty acids (NEFA), glycerol, growth hormone (GH), epinephrine (Epi), and norepinephrine (NE) were measured at baseline, mid-RE, and post-RE. Lipolysis (dialysate glycerol concentration) was elevated post-RE (baseline: 596.7 ± 82.8, post-RE: 961.4 ± 116.3 µM, P = 0.01). Energy expenditure (baseline: 1,560 ± 49; post-RE: 1,756 ± 68 kcal/day; P = 0.02) and fat oxidation (baseline: 5.64 ± 0.24; post-RE: 7.57 ± 0.41 g/h; P = 0.0003) were elevated post-RE. GH (baseline: 513.1 ± 147.4; mid-RE: 1,288.3 ± 83.9; post-RE: 1,522.8 ± 51.1 pg/ml, P = 0.000), Epi (baseline: 23.2 ± 2.7; mid-RE: 92.5 ± 16.6; post-RE: 84.5 ± 21.4 pg/ml, P = 0.000), and NE (baseline: 139.2 ± 13.6; mid-RE: 850.9 ± 155.3; post-RE: 695.3 ± 93.5 pg/ml, P = 0.000) were higher at mid-RE and post-RE. Therefore, one of the potential mechanisms behind RE-induced fat mass changes in resistance-trained women may be in part due to the accumulated effect of transient increases in SCAAT lipolysis, fat oxidation, and energy expenditure, mediated by GH, Epi, and NE release.
这项研究调查了急性全身抵抗运动[RE；一组 10 次重复，强度为 40%1 次重复最大值（1RM），三组 10 次重复，强度为 65%1RM]对年轻（年龄：22±1 岁）、正常体重和体脂率（体重指数：20±1kg/m；%体脂：28.7±1.4%）的受过阻力训练的女性的皮下腹部脂肪组织（SCAAT）脂肪分解和全身底物氧化的影响。微透析用于在基线、RE 中期、RE 后和 RE 后 30 分钟测量 SCAAT 脂肪分解，间接热量法用于在基线和 RE 后立即测量全身底物氧化在 13 名女性中进行。在基线、RE 中期和 RE 后测量血浆葡萄糖、胰岛素、非酯化脂肪酸（NEFA）、甘油、生长激素（GH）、肾上腺素（Epi）和去甲肾上腺素（NE）的浓度。RE 后脂肪分解（透析液甘油浓度）升高（基线：596.7±82.8，RE 后：961.4±116.3µM，P=0.01）。RE 后能量消耗（基线：1560±49；RE 后：1756±68 千卡/天；P=0.02）和脂肪氧化（基线：5.64±0.24；RE 后：7.57±0.41g/h；P=0.0003）升高。RE 后 GH（基线：513.1±147.4；RE 中期：1288.3±83.9；RE 后：1522.8±51.1pg/ml，P=0.000）、Epi（基线：23.2±2.7；RE 中期：92.5±16.6；RE 后：84.5±21.4pg/ml，P=0.000）和 NE（基线：139.2±13.6；RE 中期：850.9±155.3；RE 后：695.3±93.5pg/ml，P=0.000）在 RE 中期和 RE 后更高。因此，在受过阻力训练的女性中，RE 引起的脂肪量变化的潜在机制之一可能部分归因于 SCAAT 脂肪分解、脂肪氧化和能量消耗的短暂增加的累积效应，这些效应由 GH、Epi 和 NE 的释放介导。
