Brahmadathan K N, Koshi G
Department of Microbiology, Christian Medical College Hospital, Tamil Nadu, India.
J Trop Med Hyg. 1988 Dec;91(6):306-14.
A group of 89 children residing in an orphanage, situated about 12 km from Vellore town, Tamil Nadu, India, were surveyed for streptococcal pyoderma, every month, from October 1976 through to December 1978. The prevalence rate of pyoderma as defined by the isolation of group A streptococci (GAS) was 10.1% with monthly variations from 2.1% to 17.1%. Three meteorological data, namely, temperature, humidity and rainfall did not show any significant relationship with seasonal patterns of pyoderma. However, a hot and humid climate, prevalent for most of the year in Vellore, may be linked to the endemicity of this condition. Studies performed on a limited number of GAS strains showed a variety of M types in the lesions. During this survey, poststreptococcal glomerulonephritis (PSGN) was not detected. In one child, a moderate albuminuria was observed; this resolved subsequently. We attest that an active surveillance of detection and treatment of pyoderma in a highly susceptible population plays an important role in the prevention of PSGN.
1976年10月至1978年12月期间，每月对居住在印度泰米尔纳德邦韦洛尔镇约12公里外一家孤儿院的89名儿童进行链球菌性脓疱病调查。以A组链球菌（GAS）分离定义的脓疱病患病率为10.1%，每月变化范围为2.1%至17.1%。温度、湿度和降雨量这三个气象数据与脓疱病的季节模式均无显著关系。然而，韦洛尔一年中大部分时间盛行的炎热潮湿气候可能与这种疾病的地方性流行有关。对有限数量的GAS菌株进行的研究表明，病变中有多种M型。在本次调查中，未检测到链球菌感染后肾小球肾炎（PSGN）。在一名儿童中观察到中度蛋白尿，随后蛋白尿消失。我们证明，在高度易感人群中积极监测脓疱病的检测和治疗在预防PSGN方面起着重要作用。
