Gurpal-Chhabda Veenu, Singh-Chhabda Gurpal
3rd year MDS student, Department of Oral Medicine and Radiodiagnosis, Maitri Dental College and research, Anjora, Durg, C.G.
Consultant Plastic and Reconstructive Surgery, Shri Balaji Superspeciality Hospital, Raipur, C.G.
J Clin Exp Dent. 2018 Nov 1;10(11):e1127-e1129. doi: 10.4317/jced.54953. eCollection 2018 Nov.
The Van der Woude syndrome is a rare autosomal dominant development malformation characterized by a paramedian lip pits and /or sinuses or conical elevation of lower lip associated with cleft lip and or palate. These congenital lip pits usually appear clinically in the vermilion border of lip, with or without secretion. The critical region of VWS has been identified to be at Iq32 to 41 with high, but incomplete penetrance and variable expressivity. Therapeutic intervention is generally required for cosmetic reason or when recurrent inflammation is present. Dental surgeon should be aware of this syndrome, as it is associated with variety of other congenital malformation. van der woude syndrome can be easily missed if it is not in the back of mind and its associated congenital malformation if present. We report a case of lower lip pits with bilateral cleft lip. Van der Woude Syndrome, congenital pits, cleft lip / palate.
范德伍德综合征是一种罕见的常染色体显性发育畸形，其特征为旁正中唇凹和/或窦道，或下唇的圆锥形隆起，并伴有唇裂和/或腭裂。这些先天性唇凹通常在临床上出现在唇红缘，有或无分泌物。已确定范德伍德综合征的关键区域位于1q32至41，其外显率高但不完全，且表现度可变。出于美容原因或出现反复炎症时，通常需要进行治疗干预。牙科医生应了解这种综合征，因为它与多种其他先天性畸形有关。如果不牢记范德伍德综合征及其相关的先天性畸形（若存在），则很容易漏诊。我们报告一例伴有双侧唇裂的下唇凹病例。范德伍德综合征、先天性凹、唇裂/腭裂。
