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HLA-B*5701 and HLA-B*5801 in an Indian patient with anti-epileptics induced cutaneous adverse drug reactions.

作者信息

Manoharan Aarthi, Kumar Ajay Sam, Sreedevi Ambujam, Sathishkannan Aruna Devi, Gaddam Bhargav Kiran

机构信息

Central Inter-Disciplinary Research Facility, Sri Balaji Vidyapeeth (Deemed-to-be University), Puducherry, India.

Department of General Medicine, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth (Deemed-to-be University), Puducherry, India.

出版信息

Eur J Clin Pharmacol. 2019 Apr;75(4):599-601. doi: 10.1007/s00228-018-02618-5. Epub 2019 Jan 4.

DOI:10.1007/s00228-018-02618-5
PMID:30607451
Abstract
摘要

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HLA-B*5701 and HLA-B*5801 in an Indian patient with anti-epileptics induced cutaneous adverse drug reactions.一名印度患者抗癫痫药物诱发皮肤不良反应中的HLA - B*5701和HLA - B*5801
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2
Carbamazepine and phenytoin induced Stevens-Johnson syndrome is associated with HLA-B*1502 allele in Thai population.在泰国人群中，卡马西平和苯妥英钠诱发的史蒂文斯-约翰逊综合征与HLA-B*1502等位基因相关。
Epilepsia. 2008 Dec;49(12):2087-91. doi: 10.1111/j.1528-1167.2008.01719.x. Epub 2008 Jul 14.
3
Clinical application of pharmacogenomics: the example of HLA-based drug-induced toxicity.药物基因组学的临床应用：以基于人类白细胞抗原的药物性毒性为例。
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Epilepsia. 2016 Oct;57(10):e205-e209. doi: 10.1111/epi.13498. Epub 2016 Aug 16.
6
Association of cutaneous adverse drug reactions due to antiepileptic drugs with HLA alleles in a North Indian population.在印度北部人群中，与抗癫痫药物相关的皮肤不良反应与 HLA 等位基因有关。
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HLA-B∗ 1502 is associated with carbamazepine induced Stevens-Johnson syndrome in North Indian population.HLA - B∗1502与北印度人群中卡马西平诱发的史蒂文斯-约翰逊综合征相关。
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本文引用的文献

1
Association of Human Leukocyte Antigen Class 1 genes with Stevens Johnson Syndrome with severe ocular complications in an Indian population.人类白细胞抗原 1 类基因与 Stevens Johnson 综合征伴严重眼部并发症的关联在印度人群中的研究。
Sci Rep. 2017 Nov 21;7(1):15960. doi: 10.1038/s41598-017-15965-7.
2
Absence of HLA-B*1502 and HLA-A*3101 alleles in 9 Korean patients with antiepileptic drug-induced skin rash: a preliminary study.9例韩国抗癫痫药物所致皮疹患者中HLA-B*1502和HLA-A*3101等位基因缺失：一项初步研究。
Ann Lab Med. 2014 Sep;34(5):372-5. doi: 10.3343/alm.2014.34.5.372. Epub 2014 Aug 21.
3
Genetic variants associated with phenytoin-related severe cutaneous adverse reactions.
与苯妥英相关的严重皮肤不良反应相关的遗传变异。
JAMA. 2014 Aug 6;312(5):525-34. doi: 10.1001/jama.2014.7859.
4
HLA-A*31:01 and different types of carbamazepine-induced severe cutaneous adverse reactions: an international study and meta-analysis.HLA-A*31:01 与不同类型卡马西平诱导的严重皮肤不良反应：一项国际研究和荟萃分析。
Pharmacogenomics J. 2014 Jun;14(3):281-8. doi: 10.1038/tpj.2013.40. Epub 2013 Dec 10.
5
HLA-A 31:01 and HLA-B 15:02 as genetic markers for carbamazepine hypersensitivity in children.HLA-A 31:01 和 HLA-B 15:02 作为儿童卡马西平过敏的遗传标志物。
Clin Pharmacol Ther. 2013 Jul;94(1):142-9. doi: 10.1038/clpt.2013.55. Epub 2013 Mar 18.
6
Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" Problem.细胞色素 P450 3A4 的药物基因组学：朝着“缺失遗传力”问题的最新进展。
Front Genet. 2013 Feb 25;4:12. doi: 10.3389/fgene.2013.00012. eCollection 2013.
7
Carbamazepine-induced toxic effects and HLA-B*1502 screening in Taiwan.台湾的卡马西平诱导的毒性作用和 HLA-B*1502 筛查。
N Engl J Med. 2011 Mar 24;364(12):1126-33. doi: 10.1056/NEJMoa1009717.
8
HLA-B*1511 is a risk factor for carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients.HLA-B*1511 是日本患者发生卡马西平诱导的 Stevens-Johnson 综合征和中毒性表皮坏死松解症的风险因素。
Epilepsia. 2010 Dec;51(12):2461-5. doi: 10.1111/j.1528-1167.2010.02766.x. Epub 2010 Nov 3.
9
Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population.全基因组关联研究发现 HLA-A*3101 等位基因是日本人群卡马西平诱导皮肤不良反应的遗传风险因素。
Hum Mol Genet. 2011 Mar 1;20(5):1034-41. doi: 10.1093/hmg/ddq537. Epub 2010 Dec 10.
10
Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese.汉族人群芳香族抗癫痫药物诱导的 Stevens-Johnson 综合征和中毒性表皮坏死松解症的常见风险等位基因。
Pharmacogenomics. 2010 Mar;11(3):349-56. doi: 10.2217/pgs.09.162.