Institute of Intelligent Machines, Chinese Academy of Sciences, Anhui, Hefei 230031, China.
Analyst. 2019 Jan 21;144(2):421-425. doi: 10.1039/c8an02206b. Epub 2019 Jan 4.
We demonstrated a surface-enhanced Raman spectroscopy (SERS) nanoprobe, neocuproine-Cu (Nc-Cu)-functionalized Au-Ag "nanobowls" (Au-Ag NBs/Nc-Cu), for detection of glutathione (GSH). Detection was accomplished with alternation of SERS spectra from Nc-Cu into Nc-Cu resulting from the reaction of GSH with Nc-Cu on Au-Ag NBs. This nanoprobe exhibited high selectivity and sensitivity (μM) towards GSH.
我们展示了一种基于表面增强拉曼光谱（SERS）的纳米探针，即邻菲啰啉-Cu（Nc-Cu）功能化的 Au-Ag“纳米碗”（Au-Ag NBs/Nc-Cu），用于检测谷胱甘肽（GSH）。检测是通过交替出现的 Nc-Cu 的 SERS 光谱来实现的，这是由于 GSH 与 Au-Ag NBs 上的 Nc-Cu 反应所致。该纳米探针对 GSH 表现出高选择性和灵敏度（μM）。
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