替比夫定致肌病：FDG PET/CT 成像偶然发现肝癌病史患者。

Telbivudine-Induced Myopathy Incidentally Detected by FDG PET/CT Imaging in a Patient With History of Hepatocellular Carcinoma.

机构信息

From the Department of Nuclear Medicine and PET/CT, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

出版信息

Clin Nucl Med. 2019 Feb;44(2):171-172. doi: 10.1097/RLU.0000000000002385.

DOI:10.1097/RLU.0000000000002385

PMID:30608913

Abstract

Myopathy is an adverse effect of telbivudine. We describe a case of telbivudine-induced myopathy visualized on FDG PET/CT in a 75-year-old man with history of chronic HBV infection and hepatocellular carcinoma. FDG PET/CT images demonstrate no abnormal uptake characteristic of hypermetabolic malignancy. However, intense hypermetabolic activity in muscles of the abdominal wall was noted. Three months after telbivudine withdrawal, a second FDG PET/CT showed normal muscle activity in the abdominal wall.

摘要

肌病是替比夫定的一种不良反应。我们描述了一例 75 岁男性慢性乙型肝炎病毒感染和肝细胞癌患者，替比夫定诱导的肌病在 FDG PET/CT 上的表现。FDG PET/CT 图像未见高代谢恶性肿瘤的异常摄取特征。然而，注意到腹壁肌肉有强烈的高代谢活性。替比夫定停药 3 个月后，第二次 FDG PET/CT 显示腹壁肌肉的活动正常。