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带有有偏协变量和错误分类结局的加权因果推断方法。

Weighted causal inference methods with mismeasured covariates and misclassified outcomes.

机构信息

Department of Statistics and Actuarial Science, University of  Waterloo, Waterloo, Ontario, Canada.

出版信息

Stat Med. 2019 May 10;38(10):1835-1854. doi: 10.1002/sim.8073. Epub 2019 Jan 4.

Abstract

Inverse probability weighting (IPW) estimation has been widely used in causal inference. Its validity relies on the important condition that the variables are precisely measured. This condition, however, is often violated, which distorts the IPW method and thus yields biased results. In this paper, we study the IPW estimation of average treatment effects for settings with mismeasured covariates and misclassified outcomes. We develop estimation methods to correct for measurement error and misclassification effects simultaneously. Our discussion covers a broad scope of treatment models, including typically assumed logistic regression models and general treatment assignment mechanisms. Satisfactory performance of the proposed methods is demonstrated by extensive numerical studies.

摘要

逆概率加权(Inverse Probability Weighting,简称 IPW)估计在因果推断中得到了广泛应用。它的有效性依赖于变量被精确测量的重要条件。然而,这个条件经常被违反,这会扭曲 IPW 方法,从而导致有偏差的结果。在本文中,我们研究了在有协变量测量误差和结局分类错误的情况下,平均处理效应的 IPW 估计。我们开发了同时纠正测量误差和分类错误影响的估计方法。我们的讨论涵盖了广泛的治疗模型范围,包括通常假设的逻辑回归模型和一般的治疗分配机制。通过广泛的数值研究证明了所提出方法的良好性能。

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