Egui Rojo María Alejandra, Redón Gálvez Laura, Álvarez Ardura Manuel, Otaola Arca Hugo, Páez Borda Alvaro
Servicio de Urología, Hospital Universitario de Fuenlabrada, Fuenlabrada, Madrid, España.
Servicio de Urología, Hospital Universitario de Torrejón, Torrejón de Ardoz, Madrid, España.
Rev Int Androl. 2020 Apr-Jun;18(2):43-49. doi: 10.1016/j.androl.2018.07.008. Epub 2019 Jan 3.
To assess the effects of monopolar transurethral resection of the prostate (M-TURP) and bipolar TURP (B-TURP) on overall sexual function.
From December 2014 to September 2016, 100 eligible candidates with benign prostatic hyperplasia were prospectively recruited and randomized 1:1 into M-TURP/B-TURP arms (58 and 42 patients, respectively) and followed up at 1, 3 and 6 months. A univariate and multivariate analyses using the chi-squared test and a logistic regression model were performed. We recorded the age, medical conditions such as hypertension and diabetes, history of smoking, preoperative prostatic volume, prostatic symptoms scale, sexual function assessment, surgeon experience, resected grams, percentage of resected tissue and presence of retrograde ejaculation. Prostatic symptoms and erectile function (EF) assessment were quantified using self-administered IPSS scores and IIEF-5, respectively, at baseline and in each subsequent visit.
Mean age was 66 years (50-82). No statistical differences were found between both groups regarding medical comorbidities, preoperative IPSS and IIEF-5. Mean prostatic volume was 37.2 cm (10-68) and mean amount of resected tissue was 11.75g (6-58). At baseline 77,6% of patients has severe LUTS, and 50% has moderate-severe erectile dysfunction. Univariate analyses show that in both groups, history of diabetes mellitus, age and preoperative IIEF-5 were associated with poor EF. However, multivariate analyses revealed that age was the only factor associated with a poor EF. These results were similar at 3 and 6 postoperative months. We did not find an association between surgeon experience, source of energy employed or percentage of resected tissue with the development of postoperative retrograde ejaculation (52%). At first postoperative month, 44% of patients were still referring moderate prostatic symptoms and 50% had severe erectile dysfunction maintained at 6 months in both groups.
There were no differences between the source of energy employed and changes on overall sexual function. Age is the only factor associated with a poor EF status.
评估经尿道前列腺单极电切术(M-TURP)和双极电切术(B-TURP)对整体性功能的影响。
2014年12月至2016年9月,前瞻性招募了100例符合条件的良性前列腺增生患者,并按1:1随机分为M-TURP组/B-TURP组(分别为58例和42例患者),并在1、3和6个月时进行随访。使用卡方检验和逻辑回归模型进行单因素和多因素分析。我们记录了年龄、高血压和糖尿病等疾病情况、吸烟史、术前前列腺体积、前列腺症状量表、性功能评估、外科医生经验、切除重量、切除组织百分比以及逆行射精情况。在基线及每次后续随访时,分别使用患者自评的国际前列腺症状评分(IPSS)和国际勃起功能指数-5(IIEF-5)对前列腺症状和勃起功能(EF)进行量化评估。
平均年龄为66岁(50-82岁)。两组在合并症、术前IPSS和IIEF-5方面未发现统计学差异。平均前列腺体积为37.2 cm³(10-68 cm³),平均切除组织量为11.75g(6-58g)。基线时,77.6%的患者有严重下尿路症状(LUTS),50%的患者有中度至重度勃起功能障碍。单因素分析显示,在两组中,糖尿病史、年龄和术前IIEF-5与勃起功能差有关。然而,多因素分析显示年龄是与勃起功能差相关的唯一因素。术后3个月和6个月时结果相似。我们未发现外科医生经验、所使用的能量来源或切除组织百分比与术后逆行射精的发生(52%)之间存在关联。术后第一个月,44%的患者仍有中度前列腺症状,两组在6个月时均有50%的患者存在严重勃起功能障碍。
所使用的能量来源与整体性功能变化之间没有差异。年龄是与勃起功能差状态相关的唯一因素。