Schebsdat Erik, Kohl Manuel C, Corona-Strauss Farah I, Seidler Harald, Strauss Daniel J
Systems Neuroscience & Neurotechnology Unit, Saarland University, Faculty of Medicine, Homburg/Saar and Saarland University of Applied Sciences, Saarbruecken.
Key Numerics GmbH, Saarbruecken.
Audiol Res. 2018 Dec 7;8(2):216. doi: 10.4081/audiores.2018.216. eCollection 2018 Oct 2.
The importance of binaural cues in auditory stream formation and sound source segregation is widely accepted. When treating one ear with a cochlear implant (CI) the peripheral auditory system gets partially replaced and processing delays get added potentially, thus important interaural time differences get altered. However, these effects are not fully understood, leaving a lack of systematic binaural fitting strategies with respect to an optimal binaural fusion. To get new insights into such alterations, we suggest a novel method of free-field auditory brainstem evoked responses (ABRs) analysis in CI users. This method does not bypass the technically induced intrinsic delays of the sound processor while leaving the whole electrode array active, thus the most natural way of stimulation is provided. We compared the ABRs collected of 12 CI users and 12 normal hearing listeners using two different stimuli (chirp, click) at four different intensities each. We analyzed the ABRs using the average of 2000 trials as well as a single trial analysis and found consistent results in the ABRs' amplitudes and latencies, as well as in single trial relationships between both groups. This method provides a new perspective into the natural CI users' ABRs and can be useful in future research regarding binaural interaction and fusion.
双耳线索在听觉流形成和声源分离中的重要性已被广泛认可。当用人工耳蜗(CI)治疗一只耳朵时,外周听觉系统会部分被替代,并且可能会增加处理延迟,从而重要的双耳时间差异会被改变。然而,这些影响尚未完全被理解,导致缺乏关于最佳双耳融合的系统性双耳选配策略。为了深入了解此类改变,我们提出了一种针对CI使用者的自由场听觉脑干诱发电位(ABR)分析的新方法。该方法不会绕过声音处理器技术上导致的固有延迟,同时使整个电极阵列保持活跃,因此提供了最自然的刺激方式。我们比较了12名CI使用者和12名正常听力听众在四种不同强度下使用两种不同刺激(啁啾声、咔嗒声)收集的ABR。我们使用2000次试验的平均值以及单次试验分析来分析ABR,发现在ABR的幅度和潜伏期以及两组之间的单次试验关系方面结果一致。这种方法为自然状态下CI使用者的ABR提供了新的视角,并且在未来关于双耳相互作用和融合的研究中可能会有用。