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The different path of T790M-positive EGFR-mutant lung cancer.

作者信息

Yoon Shinkyo, Choi Chang Min, Lee Jae Cheol

机构信息

Department of Oncology, University of Ulsan College of Medicine, Asan Medical Center, Songpa-gu, Seoul, Korea.

Department of Pulmonary and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, Songpa-gu, Seoul, Korea.

出版信息

Ann Transl Med. 2018 Nov;6(Suppl 1):S47. doi: 10.21037/atm.2018.10.01.

DOI:10.21037/atm.2018.10.01
PMID:30613622
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6291558/
Abstract
摘要

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本文引用的文献

1
Osimertinib in Untreated EGFR-Mutated Advanced Non-Small-Cell Lung Cancer.奥希替尼治疗未经治疗的 EGFR 突变型晚期非小细胞肺癌。
N Engl J Med. 2018 Jan 11;378(2):113-125. doi: 10.1056/NEJMoa1713137. Epub 2017 Nov 18.
2
Understanding and targeting resistance mechanisms in NSCLC.了解和靶向非小细胞肺癌的耐药机制。
Nat Rev Cancer. 2017 Oct 25;17(11):637-658. doi: 10.1038/nrc.2017.84.
3
Clinical Implications of the T790M Mutation in Disease Characteristics and Treatment Response in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small-Cell Lung Cancer (NSCLC).表皮生长因子受体（EGFR）突变型非小细胞肺癌（NSCLC）患者中 T790M 突变对疾病特征和治疗反应的临床意义
Clin Lung Cancer. 2018 Jan;19(1):e19-e28. doi: 10.1016/j.cllc.2017.06.004. Epub 2017 Jun 20.
4
Targeting the Gatekeeper: Osimertinib in EGFR T790M Mutation-Positive Non-Small Cell Lung Cancer.靶向“守门员”：奥希替尼治疗 EGFR T790M 突变阳性非小细胞肺癌。
Clin Cancer Res. 2017 Feb 1;23(3):618-622. doi: 10.1158/1078-0432.CCR-15-2815. Epub 2016 Nov 7.
5
Mechanisms of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Resistance and Strategies to Overcome Resistance in Lung Adenocarcinoma.肺腺癌中表皮生长因子受体酪氨酸激酶抑制剂耐药机制及克服耐药的策略
Tuberc Respir Dis (Seoul). 2016 Oct;79(4):248-256. doi: 10.4046/trd.2016.79.4.248. Epub 2016 Oct 5.
6
Activation of the IGF1R pathway potentially mediates acquired resistance to mutant-selective 3rd-generation EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer.胰岛素样生长因子1受体（IGF1R）通路的激活可能介导晚期非小细胞肺癌对突变选择性第三代表皮生长因子受体酪氨酸激酶抑制剂产生获得性耐药。
Oncotarget. 2016 Apr 19;7(16):22005-15. doi: 10.18632/oncotarget.8013.
7
Reduced chemotherapy sensitivity in EGFR-mutant lung cancer patient with frontline EGFR tyrosine kinase inhibitor.一线使用表皮生长因子受体（EGFR）酪氨酸激酶抑制剂的EGFR突变型肺癌患者化疗敏感性降低
Lung Cancer. 2014 Nov;86(2):219-24. doi: 10.1016/j.lungcan.2014.09.008. Epub 2014 Sep 18.
8
T790M mutation is associated with better efficacy of treatment beyond progression with EGFR-TKI in advanced NSCLC patients.T790M 突变与晚期 NSCLC 患者在 EGFR-TKI 治疗进展后更好的疗效相关。
Lung Cancer. 2014 Jun;84(3):295-300. doi: 10.1016/j.lungcan.2014.03.011. Epub 2014 Mar 15.
9
Treatment of Non-small Cell Lung Carcinoma after Failure of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor.表皮生长因子受体酪氨酸激酶抑制剂治疗失败后的非小细胞肺癌治疗。
Cancer Res Treat. 2013 Jun;45(2):79-85. doi: 10.4143/crt.2013.45.2.79. Epub 2013 Jun 30.
10
Optimization of dosing for EGFR-mutant non-small cell lung cancer with evolutionary cancer modeling.基于进化癌症建模的 EGFR 突变型非小细胞肺癌给药优化。
Sci Transl Med. 2011 Jul 6;3(90):90ra59. doi: 10.1126/scitranslmed.3002356.