非裔美国人基底细胞癌的临床特征：单所学术机构的 10 年回顾性研究。

Clinical Characteristics of Basal Cell Carcinoma in African Americans: A 10-Year Retrospective Review at a Single Academic Institution.

机构信息

Department of Medicine, Division of Dermatology, Washington University in St. Louis, St. Louis, Missouri.

The Dermatology Center of Indiana, Plainfield, Indiana.

出版信息

Dermatol Surg. 2019 May;45(5):660-665. doi: 10.1097/DSS.0000000000001744.

DOI:10.1097/DSS.0000000000001744

PMID:30614839

Abstract

BACKGROUND

Basal cell carcinoma (BCC) is an uncommon diagnosis in African Americans, and as a result, there is a limited amount of data available.

OBJECTIVE

We sought to describe the clinical characteristics of BCC in African Americans treated with Mohs micrographic surgery (MMS).

METHODS

We performed a retrospective case series in an ambulatory referral center at a single academic institution from 2007 to 2017 to characterize BCCs in African Americans treated with MMS.

RESULTS

A total of 17 patients, who identified as black or African American, with 18 BCCs were included for analysis. Patients were predominantly female (82%) with a mean age at diagnosis of 61 years. Seventy-eight percent of tumors were located in the head and neck region with 50% of BCCs located in high-risk areas. The average preoperative and postoperative defect size was 1.78 and 5.90 cm, respectively, with a mean number of 2.2 Mohs stages required for tumor clearance. One patient had Gorlin syndrome.

CONCLUSION

The presented retrospective review adds to limited available reported studies regarding BCC in African Americans to potentially aid in early recognition of these tumors.

摘要

背景

基底细胞癌（BCC）在非裔美国人中是一种罕见的诊断，因此，可用的数据有限。

目的

我们旨在描述接受 Mohs 显微外科手术（MMS）治疗的非裔美国人的 BCC 临床特征。

方法

我们在 2007 年至 2017 年期间，在一家学术机构的门诊转诊中心进行了一项回顾性病例系列研究，以描述接受 MMS 治疗的非裔美国人的 BCC。

结果

共纳入 17 名自认为是黑人或非裔美国人的患者，他们共有 18 个 BCC 进行了分析。患者以女性为主（82%），平均诊断年龄为 61 岁。78%的肿瘤位于头颈部，50%的 BCC 位于高危区域。术前和术后的平均缺损大小分别为 1.78cm 和 5.90cm，需要清除肿瘤的 Mohs 阶段平均为 2.2 个。有 1 例患者患有 Gorlin 综合征。