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经阴道袋状阴道瘘的最佳手术治疗方法是什么?

What Is the Best Surgical Treatment of Pouch-Vaginal Fistulas?

机构信息

Department of Colorectal Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, Ohio.

出版信息

Dis Colon Rectum. 2019 May;62(5):595-599. doi: 10.1097/DCR.0000000000001313.

Abstract

BACKGROUND

Pouch-vaginal fistula is a debilitating condition with no single best surgical treatment described. Closure of these fistulas can be incredibly difficult, and transanal, transabdominal, and transvaginal approaches have been reported with varying success rates. Recurrence is a major problem and could eventually result in repeat redo pouch or permanent diversion.

OBJECTIVE

The aim of our study was to investigate healing rates for procedures done for pouch-vaginal fistula closure.

DESIGN

This is a retrospective analysis of a prospectively maintained database complemented by chart review.

SETTINGS

This study reports data of a tertiary referral center.

PATIENTS

Patients who underwent surgery for pouch-vaginal fistula from 2010 to 2017 were identified. Patients who underwent surgery with intent to close the fistula were included, and patients who had inadequate follow-up to verify fistula status were excluded.

INTERVENTIONS

Patients included underwent surgery to close pouch-vaginal fistula.

MAIN OUTCOME MEASURES

Success of the surgery was the main outcome measure. Success was defined as procedures with no reported recurrence of fistula on last follow-up.

RESULTS

A total of 70 patients underwent surgery with an intent to close the pouch-vaginal fistula, 65 of whom had undergone index IPAA for ulcerative colitis, but 13 of these patients later had the diagnosis changed to Crohn's disease. Thirty-nine patients (56%) had a fistula originating from anal transition zone to dentate line to the vagina (not at the pouch anastomosis). In the total group of 70 patients, our successful closure rate was 39 (56%) of 70. Procedures with the highest success rates were perineal ileal pouch advancement flap and redo IPAA (61% and 69%).

LIMITATIONS

The retrospective nature and small number of cases are the limitations of the study.

CONCLUSIONS

Although numerous procedures may be used in an attempt to close pouch-vaginal fistula, pouch advancement and redo pouch were the most successful in closing the fistula. See Video Abstract at http://links.lww.com/DCR/A841.

摘要

背景

直肠阴道瘘是一种使人虚弱的疾病,目前尚无单一的最佳手术治疗方法。这些瘘管的闭合非常困难,经肛门、经腹腔和经阴道的方法已被报道,成功率各不相同。复发是一个主要问题,最终可能导致重复造口或永久性转流。

目的

我们的研究旨在调查用于直肠阴道瘘闭合的手术的愈合率。

设计

这是一项前瞻性维护数据库的回顾性分析,并辅以图表审查。

设置

本研究报告了一个三级转诊中心的数据。

患者

从 2010 年到 2017 年,我们确定了接受直肠阴道瘘手术的患者。纳入接受手术以闭合瘘管的患者,排除随访不足以验证瘘管状态的患者。

干预措施

纳入的患者接受了闭合直肠阴道瘘的手术。

主要观察指标

手术的成功是主要观察指标。成功定义为在最后一次随访时无瘘管复发报告的手术。

结果

共有 70 名患者接受了闭合直肠阴道瘘的手术,其中 65 名患者因溃疡性结肠炎接受了首次 IPAA,但其中 13 名患者后来被诊断为克罗恩病。39 名患者(56%)的瘘管起源于肛门移行带至齿状线至阴道(不在直肠吻合口处)。在 70 名患者的总组中,我们的闭合成功率为 70 例中的 39 例(56%)。成功率最高的手术是会阴回肠袋推进皮瓣和再次 IPAA(分别为 61%和 69%)。

局限性

该研究的局限性在于回顾性研究和病例数量少。

结论

尽管有许多手术方法可用于尝试闭合直肠阴道瘘,但回肠袋推进和再次 IPAA 是闭合瘘管最成功的方法。在 http://links.lww.com/DCR/A841 上观看视频摘要。

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