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针对患有厌食症的年轻初级保健患者自动进行促甲状腺激素和铁蛋白检测,作为改善潜在疾病检测的一种干预措施。

Automated Requests for Thyroid-Stimulating Hormone and Ferretin Tests in Young Primary Care Patients with Anorexia as an Intervention to Improve Detection of Underlying Conditions.

作者信息

Salinas Maria, López-Garrigós Maite, Flores Emilio, Leiva-Salinas Carlos

机构信息

Department of Biochemistry and Molecular Pathology, Universidad Miguel Hernandez, Elche, Spain.

Clinical Laboratory, Hospital Universitario de San Juan, San Juan de Alicante, Spain.

出版信息

Lab Med. 2019 Jul 16;50(3):268-272. doi: 10.1093/labmed/lmy076.

Abstract

OBJECTIVE

To improve clinical laboratory contribution to the treatment of primary care patients with anorexia through automated computerized strategies.

METHODS

We recorded the number of laboratory requests due to anorexia; the demographic data, laboratory values, and presence of pathological values for the applicable patients. In a prospective study, the laboratory information management system (LIMS) automatically added thyroid-stimulating hormone (TSH) and/or ferritin testing when it was not requested by general practitioners for all primary care patients with anorexia who were younger than 16 years.

RESULTS

A total of 3562 patients underwent laboratory testing due to anorexia, of whom 47% were younger than 16 years. The tests in which the results most frequently were abnormal were hemoglobin, ferritin, and TSH. TSH results were abnormal in 20% of patients younger than 16 years. Through the intervention, we detected 3 low ferritin values and 7 cases of pathological TSH levels.

CONCLUSIONS

The LIMS required TSH and ferritin testing in young patients even when not requested, potentially avoiding the adverse effects of iron deficiency and thyroid disorders on neurological development and cognition in those patients.

摘要

目的

通过自动化计算机策略提高临床实验室对初级保健厌食症患者治疗的贡献。

方法

我们记录了因厌食症提出的实验室检查申请数量;适用患者的人口统计学数据、实验室值以及病理值的存在情况。在一项前瞻性研究中,对于所有16岁以下患有厌食症的初级保健患者,当全科医生未要求时,实验室信息管理系统(LIMS)会自动添加促甲状腺激素(TSH)和/或铁蛋白检测。

结果

共有3562名患者因厌食症接受了实验室检查,其中47%年龄小于16岁。结果最常出现异常的检查项目是血红蛋白、铁蛋白和TSH。16岁以下患者中20%的TSH结果异常。通过干预,我们检测到3例低铁蛋白值和7例病理性TSH水平病例。

结论

即使未被要求,LIMS也对年轻患者进行TSH和铁蛋白检测,这可能避免了缺铁和甲状腺疾病对这些患者神经发育和认知的不良影响。

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