The James Cancer Hospital and Solove Research Institute, Wexner Medical Center at The Ohio State University, Department of Otolaryngology - Head and Neck Surgery, Columbus, OH, United States.
The James Cancer Hospital and Solove Research Institute, Wexner Medical Center at The Ohio State University, Department of Otolaryngology - Head and Neck Surgery, Columbus, OH, United States.
Oral Oncol. 2019 Jan;88:137-144. doi: 10.1016/j.oraloncology.2018.11.022. Epub 2018 Nov 29.
Salvage total laryngectomy is often indicated in patients with recurrent or persistent laryngeal cancer after radiation or chemoradiation treatment. This article reviews and discusses key considerations regarding salvage laryngectomy. Within this article, a review of the salvage laryngectomy incidence in the major organ preservation trials, survival rates, predictors of outcomes, complication rates, and the roles of elective neck dissection and free tissue transfer for reconstruction in patients undergoing salvage laryngectomy is provided.
挽救性全喉切除术通常适用于放射或放化疗后复发性或持续性喉癌患者。本文回顾并讨论了挽救性喉切除术的关键注意事项。本文回顾了主要器官保存试验中挽救性喉切除术的发生率、生存率、结局预测因素、并发症发生率,以及在接受挽救性喉切除术的患者中选择性颈清扫术和游离组织移植重建的作用。